389131-94-6

Basic information

• Product Name: 4-Azidobutanol 1-(4-Methylbenzenesulfonate)
• Synonyms: 4-Azidobutanol 1-(4-Methylbenzenesulfonate)
• CAS NO: 389131-94-6
• Molecular Formula: C₁₁H₁₅N₃O₃S
• Molecular Weight: 269.3201
• Product Categories: Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 389131-94-6.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• Storage Temp.: Refrigerator
• Solubility: Acetone, Chloroform, Dichloromethane, Ethyl Acetate, Methanol
• CAS DataBase Reference: 4-Azidobutanol 1-(4-Methylbenzenesulfonate)(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Azidobutanol 1-(4-Methylbenzenesulfonate)(389131-94-6)
• EPA Substance Registry System: 4-Azidobutanol 1-(4-Methylbenzenesulfonate)(389131-94-6)

Safety Data

• Hazardous Substances Data: 389131-94-6(Hazardous Substances Data)

Usage

Description

4-Azidobutanol 1-(4-Methylbenzenesulfonate) is an organic compound characterized by its colorless oil appearance. It is a derivative of 4-azidobutanol, featuring a 4-methylbenzenesulfonate group attached to it. 4-Azidobutanol 1-(4-Methylbenzenesulfonate) is known for its unique chemical properties and potential applications in various fields.

Uses

Used in Pharmaceutical Industry:
4-Azidobutanol 1-(4-Methylbenzenesulfonate) is used as an intermediate in the synthesis of sulforaphane and related isothiocyanates. These compounds have been recognized for their potential health benefits, particularly in the prevention and treatment of certain types of cancer. 4-Azidobutanol 1-(4-Methylbenzenesulfonate) plays a crucial role in the preparation process, enabling the development of these therapeutic agents.
Used in Chemical Research:
As a colorless oil with distinct chemical properties, 4-Azidobutanol 1-(4-Methylbenzenesulfonate) is also utilized in various chemical research applications. It serves as a valuable starting material for the synthesis of other complex organic molecules, contributing to the advancement of chemical science and the development of novel compounds with potential applications in various industries.

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 172468-38-1 4-azido-1-butylacetate 
• 54953-78-5 4-azido-1-butanol 

Downstream Products

• 911306-51-9 N-(4-azidobutyl)-N-benzylamine 
• 1325740-63-3 N-(4-azidobutyl)-2,3,4,6-tetra-O-benzyl-1-deoxynojirimycin 
• 57775-01-6 1-azido-(4-methylsulfenyl)butane 
• 1448811-38-8 N-(4'-azidobutyl)-2,3,4,6-tetra-O-benzyl-1-deoxygalactonojirimycin 
• 1458630-33-5 1-(4-azidobutyl)-4-(2-methoxyphenyl)piperazine 

Relevant articles and documents

Design, Synthesis, Radiosynthesis and Biological Evaluation of Fenretinide Analogues as Anticancer and Metabolic Syndrome-Preventive Agents

Fenretinide (4-HPR) is a synthetic derivative of all-trans-retinoic acid (ATRA) characterised by improved therapeutic properties and toxicological profile relative to ATRA. 4-HPR has been mostly investigated as an anti-cancer agent, but recent studies sho

One-Pot Synthesis of Trisubstituted Triazenes from Grignard Reagents and Organic Azides

A simple and versatile method for the preparation of linear, trisubstituted triazenes is reported. The procedure is based on the reaction of Grignard reagents with 1-azido-4-iodobutane or 4-azidobutyl-4-methylbenzenesulfonate. These organic azides enable the regioselective formation of triazenes via an intramolecular cyclization step. The new method can be used for the preparation of aryl, heteroaryl, vinyl, and alkyl triazenes. The synthetic utility of vinyl triazenes is demonstrated by acid-induced C-N, C-O, C-F, C-P, and C-S bond-forming reactions.

Sulforaphane and erucin, natural isothiocyanates from broccoli, inhibit bacterial quorum sensing

Sulforaphane and erucin, two natural isothiocyanates that are highly abundant in broccoli and other cruciferous vegetables, were found to strongly inhibit quorum sensing and virulence in Pseudomonas aeruginosa. Mechanistic evaluations of these effects suggest that these isothiocyanates are antagonists of the transcriptional activator LasR. The Royal Society of Chemistry 2013.