392724-96-8Relevant articles and documents
First generation design, synthesis, and evaluation of azepine-based cryptophycin analogues.
Smith 3rd.,Cho,Zawacki,Hirschmann,Pettit
, p. 4063 - 4066 (2007/10/03)
[structure: see text] Azepine-based cryptophycin mimics (+)-4 and (+)-5 have been designed and synthesized. Biological evaluation revealed modest in vitro activity against several human tumor cell lines, thereby supporting the utility of novel scaffolds for the design and synthesis of cryptophycin analogues.