39507-96-5

Basic information

• Product Name: 2-(3,5-Dimethoxyphenyl)propan-2-ol
• Synonyms: 2-(4-(3,5-DIMETHOXYPHENYL)-YL)-2-PROPANOL;2-(3,5-DIMETHOXYPHENYL)PROPAN-2-OL;DDZ-OH;3,5-dimethoxy-alpha,alpha-dimethylbenzyl alcohol;3,5-dimethoxy-2,2-dimethylbenzene methanol;3,5-Dimethoxy-α,α-dimethylbenzenemethanol;2-(3,5-dimethoxyphenyl)-2-propanol
• CAS NO: 39507-96-5
• Molecular Formula: C₁₁H₁₆O₃
• Molecular Weight: 196.24
• EINECS: 254-476-1
• Product Categories: Benzene derivates
• Mol File: 39507-96-5.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 307.1 °C at 760 mmHg
• Flash Point: 139.5 °C
• Appearance: /
• Density: 1.06 g/cm³
• Vapor Pressure: 0.000323mmHg at 25°C
• Refractive Index: 1.504
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 2-(3,5-Dimethoxyphenyl)propan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3,5-Dimethoxyphenyl)propan-2-ol(39507-96-5)
• EPA Substance Registry System: 2-(3,5-Dimethoxyphenyl)propan-2-ol(39507-96-5)

Safety Data

• Hazardous Substances Data: 39507-96-5(Hazardous Substances Data)

Usage

General Description

2-(3,5-Dimethoxyphenyl)propan-2-ol, also known as 2C-D, is a chemical compound that belongs to the phenethylamine class. It is a psychoactive substance that acts as a hallucinogen and is structurally related to mescaline. 2C-D is known for its psychedelic effects, including visual and auditory hallucinations, altered perception of time and space, and changes in mood and consciousness. It is often used recreationally for its hallucinogenic properties and is considered a controlled substance in many countries due to its potential for abuse and dependence. Research has also been conducted on its potential therapeutic applications, particularly in the treatment of certain mental health disorders.

InChI:InChI=1/C11H16O3/c1-11(2,12)8-5-9(13-3)7-10(6-8)14-4/h5-7,12H,1-4H3

Upstream product

• 2150-37-0 methyl 3,5-dimethoxybenzoate 
• 75-16-1 methylmagnesium bromide 
• 74-88-4 methyl iodide 
• 17275-82-0 ethyl 3,5-dimethoxybenzoate 
• 1132-21-4 3,5-dimethoxybenzoic acid 
• 39151-19-4 1-(3,5-dimethoxyphenyl)ethan-1-one 

Downstream Products

• 129918-80-5 ((1R,3R)-3-{[1-(3,5-Dimethoxy-phenyl)-1-methyl-ethoxycarbonylamino]-methyl}-3,5,5-trimethyl-cyclohexyl)-carbamic acid 1-(3,5-dimethoxy-phenyl)-1-methyl-ethyl ester 
• 120078-05-9 2-(3,5-dimethoxyphenyl)-2-bromopropane 
• 74385-25-4 C₂₂H₃₀O₄ 
• 129918-78-1 N-<<1-(3,5-dimethoxyphenyl)-1-methylethoxy>carbonyl>cyclohexylamine 
• 39507-99-8 3,5-dimethoxy-α,α-dimethylbenzenemethanol pentachlorophenyl carbonate ester 
• 39508-00-4 3,5-dimethoxy-α,α-dimethylbenzylcarbazate 
• 39507-97-6 (α,α-dimethyl-3,5-dimethoxybenzyl)-phenylcarbonate 
• 74385-33-4 C₁₈H₂₂O₄ 
• 74385-36-7 Acetic acid 3-acetoxy-5-[2-(3,5-diacetoxy-phenyl)-1,1,2-trimethyl-propyl]-phenyl ester 
• 73109-76-9 5-isopropyl-1,3-dimethoxybenzene 
• 120078-30-0 2-(3,5-dimethoxyphenyl)-2-methylpropanal 
• 120116-27-0 2-(3,5-Dimethoxy-phenyl)-1-(3,4-dimethoxy-phenyl)-2-methyl-propan-1-ol 
• 120078-16-2 3-(3,4-dimethoxyphenyl)-6,8-dimethoxy-4,4-dimethyl-3,4-dihydro-1(2H)-naphthalenone 
• 120078-19-5 4-(3,5-Dimethoxy-phenyl)-3-(3,4-dimethoxy-phenyl)-4-methyl-pentanoic acid methyl ester 

Relevant articles and documents

Access to "friedel-Crafts-Restricted" tert -alkyl aromatics by activation/methylation of tertiary benzylic alcohols

Herein we describe a two-step protocol to prepare m-tert-alkylbenzenes. The appropriate tertiary benzylic alcohols are activated with SOCl2 or concentrated HCl and then treated with trimethylaluminum, affording the desired products in 68-97% yields (22 examples). This reaction sequence is successful in the presence of a variety of functional groups, including acid-sensitive and Lewis-basic groups. In addition to t-Bu groups, 1,1-dimethylpropyl and 1-ethyl-1-methylpropyl groups can also be installed using this method.

SYNTHESIS OF A CARBOCYCLIC ANALOG OF QUERCETIN VIA A BARBIER REACTION

A six-step synthetic route to the carbocyclic flavonoid 2 is described.The key step involves a 1,4-addition of a tertiary bromide to a α,β-unsaturated ester by the Barbier reaction.

The , -dimethyl-3,5-dimethoxybenzyloxycarbonyl (Ddz) residue, an N-protecting group labile toward weak acids and irradiation

-