39739-03-2 Usage
Description
Methyl 4-(1,3-dioxoisoindolin-2-yl)butanoate is a chemical compound with the molecular formula C11H11NO4. It is a derivative of the 1,3-dioxoisoindolin-2-yl group, which is a heterocyclic compound containing two oxygen atoms in a five-membered ring. The butanoate group, which consists of a four-carbon chain with a terminal ester functional group, is attached to the 1,3-dioxoisoindolin-2-yl ring.
Uses
Used in Organic Synthesis:
Methyl 4-(1,3-dioxoisoindolin-2-yl)butanoate is used as a chemical intermediate in organic synthesis for the development of new compounds.
Used in Pharmaceutical Research:
Methyl 4-(1,3-dioxoisoindolin-2-yl)butanoate is used as a building block in pharmaceutical research for the development of new drugs and bioactive compounds.
Used in Chemical Production:
Methyl 4-(1,3-dioxoisoindolin-2-yl)butanoate is used as a chemical intermediate in the production of other compounds in the chemical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 39739-03-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,9,7,3 and 9 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 39739-03:
(7*3)+(6*9)+(5*7)+(4*3)+(3*9)+(2*0)+(1*3)=152
152 % 10 = 2
So 39739-03-2 is a valid CAS Registry Number.
InChI:InChI=1/C13H13NO4/c1-18-11(15)7-4-8-14-12(16)9-5-2-3-6-10(9)13(14)17/h2-3,5-6H,4,7-8H2,1H3
39739-03-2Relevant articles and documents
Oxidative damage of proline residues by nitrate radicals (NO3): A kinetic and product study
Nathanael, Joses G.,Nuske, Madison R.,Richter, Annika,White, Jonathan M.,Wille, Uta
supporting information, p. 6949 - 6957 (2020/10/02)
Tertiary amides, such as in N-acylated proline or N-methyl glycine residues, react rapidly with nitrate radicals (NO3) with absolute rate coefficients in the range of 4-7 × 108 M-1 s-1 in acetonitrile. The major pathway proceeds through oxidative electron transfer (ET) at nitrogen, whereas hydrogen abstraction is only a minor contributor under these conditions. However, steric hindrance at the amide, for example by alkyl side chains at the α-carbon, lowers the rate coefficient by up to 75%, indicating that NO3-induced oxidation of amide bonds proceeds through initial formation of a charge transfer complex. Furthermore, the rate of oxidative damage of proline and N-methyl glycine is significantly influenced by its position in a peptide. Thus, neighbouring peptide bonds, particularly in the N-direction, reduce the electron density at the tertiary amide, which slows down the rate of ET by up to one order of magnitude. The results from these model studies suggest that the susceptibility of proline residues in peptides to radical-induced oxidative damage should be considerably reduced, compared with the single amino acid.