400031-49-4Relevant articles and documents
Synthesis of some 2-thioxopyrido[2,3-d]pyrimidine ribofuranosides and their antimicrobial activity
Kumar, Neeraj,Singh, Gajendra,Yadav, Ashok K.
, p. 217 - 225 (2007/10/03)
2-Thioxo-3,5,7-trisubstituted-1-[2′,3′.5′-tri-O-benzoyl-β -D-ribofuranosyl]pyrido[2,3-d]pyri midin-4(IH)-ones have been prepared by the condensation of trimethylsilyl derivative of 2-thioxo-3,5,7-trisubstituted pyrido[2,3-d]pyrimidin-4(IH)-ones with β-D-ribofuranose 1-acetate-2,3,5-tribenzoate in 65%-78% yield. The structure of the synthesized ribofuranosides and their precursors have been established by IR. 1H NMR and elemental analysis. These derivatives have been screened for their antimicrobial activity.