400744-13-0Relevant articles and documents
Palladium(II)-catalyzed mono-and bis-alkenylation of N-acetyl-2-aminobiaryls through regioselective C-H bond activation
Annamalai, Pratheepkumar,Hsu, Kou-Chi,Raju, Selvam,Hsiao, Huan-Chang,Chou, Chih-Wei,Lin, Gu-Ying,Hsieh, Cheng-Ming,Chen, Pei-Ling,Liu, Yi-Hung,Chuang, Shih-Ching
, p. 3840 - 3856 (2018/04/14)
We developed palladium-catalyzed oxidative coupling of olefins with N-acyl 2-aminobiaryls through a sequence of ortho C-H bond activation/alkene insertion/reductive elimination. Furthermore, we controlled the selectivity of mono-and bis-alkenylation products with the solvent effect. The developed protocol was promising for a broad substrate scope ranging from activated olefins with a wide variety of functional groups to unactivated olefins.