55578-79-5

Basic information

• Product Name: 2-(2-FURYL)ANILINE
• Synonyms: AKOS BAR-0082;2-FURAN-2-YL-PHENYLAMINE;2-(2-FURYL)ANILINE;2-Fur-2-ylaniline;2-Fur-2-ylaniline 97%;2-(2-Aminophenyl)furan;2-(Fur-2-yl)aniline97%
• CAS NO: 55578-79-5
• Molecular Formula: C₁₀H₉NO
• Molecular Weight: 159.18
• Mol File: 55578-79-5.mol
• Article Data: 17

Chemical Properties

• Boiling Point: 273.5 °C at 760 mmHg
• Flash Point: 119.2 °C
• Appearance: /
• Density: 1.138 g/cm³
• Vapor Pressure: 0.0057mmHg at 25°C
• Refractive Index: 1.593
• CAS DataBase Reference: 2-(2-FURYL)ANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-FURYL)ANILINE(55578-79-5)
• EPA Substance Registry System: 2-(2-FURYL)ANILINE(55578-79-5)

Safety Data

• Hazardous Substances Data: 55578-79-5(Hazardous Substances Data)

Usage

General Description

2-(2-furyl)aniline, also known as 2-aminobenzofuran, is an organic compound with the chemical formula C10H9NO. It consists of a benzene ring with a furan ring and an amino group attached to it. It is used in the production of dyes, pharmaceuticals, and other organic compounds. The presence of both the furan and amino groups makes it a versatile building block for chemical synthesis. It is also used in the production of antimalarial drugs and as an intermediate in the synthesis of other important organic compounds. This chemical is considered to be a skin and eye irritant and should be handled with care.

InChI:InChI=1/C10H9NO/c11-9-5-2-1-4-8(9)10-6-3-7-12-10/h1-7H,11H2

Upstream product

• 28988-02-5 2-(2-nitrophenyl)-furan 
• 13331-23-2 fur-2-ylboronic acid 
• 615-36-1 2-bromoaniline 
• 577-19-5 2-nitrophenyl bromide 
• 615-43-0 2-iodophenylamine 
• 118486-94-5 2-(tributylstannyl)furan 
• 29048-34-8 5-(2-nitrophenyl)-2-furoic acid 

Downstream Products

• 102269-45-4 2-[(2-Furan-2-yl-phenylamino)-methylene]-malonic acid diethyl ester 
• 852285-83-7 5-Cyano-furan-2-carboxylic acid (2-furan-2-yl-phenyl)-amide 
• 877231-04-4 4-cyano-N-(2-furan-2-ylphenyl)-3-methyl-benzamide 
• 1182844-54-7 4-phenylfuro[3,2-c]quinoline 
• 1352548-18-5 N-[2-(2-furyl)phenyl]-4-methylbenzenesulfonamide 
• 1359768-78-7 N-allyl-2-(2-furyl)aniline 
• 1359768-85-6 N,N-diallyl-2-(2-furyl)aniline 
• 221230-45-1 2-(2-furyl)-1-ethynylbenzene 
• 221230-61-1 ((2-(furan-2-yl)phenyl)ethynyl)trimethylsilane 
• 400744-13-0 N-(2-(furan-2-yl)phenyl)acetamide 
• 55578-83-1 2-(2-azidophenyl)furan 
• 55077-51-5 4H-furo[3,2-b]indole 

Relevant articles and documents

Gold-Catalyzed Cascade Reactions of 4 H-Furo[3,2-b]indoles with Allenamides: Synthesis of Indolin-3-one Derivatives

Merging the ability of cationic gold(I) catalysts to activate unsaturated π-systems with the electrophiles-driven ring-opening reactions of furans, we describe a new approach to synthesize 2-spiroindolin-3-ones from 4H-furo[3,2-b]indoles. The reaction occ

Rhodium(I)-Catalyzed Aryl C-H Carboxylation of 2-Arylanilines with CO2

An unprecedented Rh(I)-catalyzed, amino-group-assisted C-H carboxylation of 2-arylanilines with CO2 under redox-neutral conditions has been developed. This reaction was promoted by a phosphine ligand with t-BuOK as the base and did not require the use of additional strong organometallic reagent. It enabled an efficient direct conversion of a broad range of 2-(hetero)arylanilines including electron-deficient heteroarenes to various phenanthridinones. Possible intermediates of the reaction were also evaluated in the preliminary mechanistic studies.

Pd/Cu-Catalyzed aerobic oxidative aromatic C-H bond activation/N-dealkylative carbonylation towards the synthesis of phenanthridinones

It is important to achieve diverse functionalization of tertiary anilines due to their importance in biological molecules, pharmaceutical, functional materials, and ligands. A straightforward Pd/Cu-catalyzed oxidative C-H bond activation/N-dealkylative carbonylation of tertiary [1,1′-biphenyl]-2-anilines towards the synthesis of various biologically important phenanthridin-6(5H)-ones has been developed. A wide range of functional groups are well tolerated in this transformation. Moreover, O2 is utilized as the terminal oxidant to promote the oxidative carbonylation process.