401-75-2

Basic information

• Product Name: (TRIFLUOROMETHYL)CYCLOHEXANE
• Synonyms: (TRIFLUOROMETHYL)CYCLOHEXANE
• CAS NO: 401-75-2
• Molecular Formula: C₇H₁₁F₃
• Molecular Weight: 152.16
• Mol File: 401-75-2.mol
• Article Data: 19

Chemical Properties

• Boiling Point: 107°C(lit.)
• Flash Point: 10°C
• Appearance: /
• Density: 1.09g/cm³
• Vapor Pressure: 36.7mmHg at 25°C
• Refractive Index: 1.3730 and le 1.3770
• CAS DataBase Reference: (TRIFLUOROMETHYL)CYCLOHEXANE(CAS DataBase Reference)
• NIST Chemistry Reference: (TRIFLUOROMETHYL)CYCLOHEXANE(401-75-2)
• EPA Substance Registry System: (TRIFLUOROMETHYL)CYCLOHEXANE(401-75-2)

Safety Data

• Statements: 11-36/37/38
• Safety Statements: 16-26-36/37/39
• RIDADR: 1993
• HazardClass: 3
• PackingGroup: II
• Hazardous Substances Data: 401-75-2(Hazardous Substances Data)

Usage

General Description

(TRIFLUOROMETHYL)CYCLOHEXANE is a colorless liquid with the chemical formula C7H11F3. It is a fluorinated derivative of cyclohexane and is used as a solvent and intermediate in chemical synthesis. It has a boiling point of 92-96°C and is insoluble in water but soluble in organic solvents. (TRIFLUOROMETHYL)CYCLOHEXANE is known for its low toxicity and non-flammability, making it a relatively safe chemical to handle. It is commonly used in the production of pharmaceuticals, agrochemicals, and materials like polymers and coatings. Additionally, it can be used in the synthesis of other fluorinated compounds due to its unique chemical properties.

InChI:InChI=1/C7H11F3/c8-7(9,10)6-4-2-1-3-5-6/h6H,1-5H2

Upstream product

• 98-17-9 3-Trifluoromethylphenol 
• 98-89-5 Cyclohexanecarboxylic acid 
• 108-85-0 1-bromocyclohexane 
• 683-98-7 methyl bromodifluoroacetate 
• 98-08-8 α,α,α-trifluorotoluene 
• 402-45-9 4-hydroxybenzotrifluoride 
• 76-05-1 trifluoroacetic acid 
• 542-18-7 cyclohexyl chloride 
• 383-64-2 S-ethyl trifluoroacetate 
• 110-83-8 cyclohexene 
• 60933-15-5 phenyl trifluoromethanethiosulfonate 
• 454-55-7 1-(trifluoromethyl)-1-cyclohexene 
• 108-94-1 cyclohexanone 
• 80768-55-4 1-(trifluoromethyl)-1-cyclohexanol 

Downstream Products

• 76-05-1 trifluoroacetic acid 
• 610-71-9 2,5-dibromobenzoic acid 
• 619-03-4 3,4-dibromobenzoic acid 
• 7664-39-3 hydrogen fluoride 
• 7732-18-5 water 
• 15719-64-9 methylammonium carbonate 
• 454-63-7 3-(trifluoromethyl)cyclohexan-1-ol 
• 75091-92-8 4-(trifluoromethyl)cyclohexan-1-ol 
• 585-36-4 3-(trifluoromethyl)cyclohexanone 
• 75091-99-5 4-(trifluoromethyl)cyclohexan-1-one 
• 696-32-2 1,1-difluoromethylenecyclohexane 
• 4410-75-7 (cyclohexylmethyl)benzene 
• 358-43-0 triethylsilyl fluoride 
• 82166-21-0 methyl cyclohexane 

Relevant articles and documents

Trifluoromethyl Thianthrenium Triflate: A Readily Available Trifluoromethylating Reagent with Formal CF3+, CF3?, and CF3-Reactivity

Here we report the synthesis and application of trifluoromethyl thianthrenium triflate (TT-CF3+OTf-) as a novel trifluoromethylating reagent, which is conveniently accessible in a single step from thianthrene and triflic anhydride. We demonstrate the use of TT-CF3+OTf- in electrophilic, radical, and nucleophilic trifluoromethylation reactions.

Mild and Selective Rhodium-Catalyzed Transfer Hydrogenation of Functionalized Arenes

Diboron-mediated rhodium-catalyzed transfer hydrogenation of functionalized arenes is reported. In addition to good functional group tolerance, the reaction features operational simplicity and controllable chemoselectivity. The general applicability of this procedure is demonstrated by the selective hydrogenation of a range of arenes, including functionalized benzenes, biphenyls, and polyaromatics.

Iterative Preparation of Platinum Nanoparticles in an Amphiphilic Polymer Matrix: Regulation of Catalytic Activity in Hydrogenation

We demonstrate that iteration of the seeded preparation of platinum nanoparticles dispersed in an amphiphilic polystyrene-poly(ethylene glycol) resin (ARP-Pt) regulates their catalytic activity in the hydrogenation of aromatic compounds in water. The catalytic activity of the fifth generation of ARP-Pt [G5] prepared through four iterations of the seeded preparation was far superior to that of the initial ARP-Pt [G1] in the hydrogenation of aromatic compounds in water.