401502-08-7 Usage
Chemical class
Piperazine derivative
Structural features
4-bromophenoxy group
Methyl substituent
Usage
Intermediate for the synthesis of pharmaceutical drugs
Pharmacological properties
Antidepressant potential
Anxiolytic potential
Anti-inflammatory potential
Receptor interaction
Dopamine D3 receptor ligand
Potential applications
Treatment of neurological disorders
Treatment of psychiatric disorders
Check Digit Verification of cas no
The CAS Registry Mumber 401502-08-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,0,1,5,0 and 2 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 401502-08:
(8*4)+(7*0)+(6*1)+(5*5)+(4*0)+(3*2)+(2*0)+(1*8)=77
77 % 10 = 7
So 401502-08-7 is a valid CAS Registry Number.
401502-08-7Relevant articles and documents
BET INHIBITORS FOR MODULATING DUX4 EXPRESSION IN FSHD
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Page/Page column 236, (2020/07/14)
The present disclosure provides BET inhibitors of the formula: wherein the variables are defined herein, as well as pharmaceutical compositions thereof. The present disclosure also provides methods of treating a patient comprising administering a bromo- and extra-terminal (BET) domain inhibitor for the treatment of FSHD which modulates DUX4 expression. In some embodiments, the present methods comprise using one or more BET inhibitors as a therapeutic agent for the treatment of FSHD patients including patients who are being treated with one or more palliative treatments such as therapy and/or agents which lead to increased muscle mass.
