40173-90-8

Basic information

• Product Name: 3 4-DIMETHOXYPHENETHYL BROMIDE
• Synonyms: 2-Methoxy-4-(2-bromoethyl)anisole, 3,4-Dimethoxy-1-(2-bromoethyl)benzene;4-(2-broMoethyl)-1,2-diMethoxybenzene;3,4-DiMethoxyphenethyl broMide 97%;LTAGXVMHLFYRNK-UHFFFAOYSA-N
• CAS NO: 40173-90-8
• Molecular Formula: C₁₀H₁₃BrO₂
• Molecular Weight: 245.11
• Mol File: 40173-90-8.mol
• Article Data: 6

Chemical Properties

• Melting Point: 52-56 °C(lit.)
• Boiling Point: 130-131 °C3 mm Hg(lit.)
• Flash Point: >230 °F
• Appearance: /
• Density: 1.336g/cm³
• Vapor Pressure: 0.005mmHg at 25°C
• Refractive Index: 1.533
• CAS DataBase Reference: 3 4-DIMETHOXYPHENETHYL BROMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3 4-DIMETHOXYPHENETHYL BROMIDE(40173-90-8)
• EPA Substance Registry System: 3 4-DIMETHOXYPHENETHYL BROMIDE(40173-90-8)

Safety Data

• Hazard Codes: Xn,N
• Statements: 22-36-50
• Safety Statements: 26-36/37-61
• RIDADR: UN 2811 6.1/PG 3
• WGK Germany: 2
• Hazardous Substances Data: 40173-90-8(Hazardous Substances Data)

Usage

General Description

3,4-Dimethoxyphenethyl bromide is a chemical compound with the molecular formula C10H13BrO2. It is a brominated derivative of 3,4-dimethoxyphenethylamine, and its structure consists of a phenyl ring with two methoxy groups and an ethylamine chain. The compound is primarily used in organic synthesis and pharmaceutical research. It is a bromide salt, commonly used as a reagent in various chemical reactions due to its ability to function as a leaving group in substitution reactions. Its chemical properties make it useful in the creation of new compounds and pharmaceutical drugs. Additionally, it has potential applications in the development of new materials and chemical processes.

InChI:InChI=1/C10H13BrO2/c1-12-9-4-3-8(5-6-11)7-10(9)13-2/h3-4,7H,5-6H2,1-2H3

Upstream product

• 18066-68-7 ethyl 3,4-dimethoxyphenylacetate 
• 558-13-4 carbon tetrabromide 
• 7417-21-2 2-(3,4-dimethoxyphenyl)ethyl alcohol 
• 75803-23-5 methanesulphonic acid,2-(3,4-dimethoxyphenyl)ethyl ester 
• 5703-21-9 3,4-dimethoxyphenylacetaldehyde 

Downstream Products

• 71642-81-4 N-[2-(3,4-dimethoxyphenyl)ethyl]piperidine 
• 132624-43-2 1-(3,4-dimethoxy-phenethyl)-2-methyl-pyridinium; bromide 
• 101864-54-4 1-(3,4-dimethoxy-phenethyl)-2,3,4,5,6,7-hexahydro-indole 
• 111473-87-1 5-ethyl-1-(3,4-dimethoxy-phenethyl)-2-methyl-pyridinium; bromide 
• 59033-40-8 1-(3,4-dimethoxy-phenethyl)-6-oxo-1,6-dihydro-pyridine-3-carboxylic acid 
• 111383-85-8 5-ethyl-1-(3,4-dimethoxy-phenethyl)-4-methoxycarbonyl-2-methyl-pyridinium; bromide 
• 123102-89-6 1-(3,4-dimethoxy-phenethyl)-3-[1,3]dioxolan-2-yl-pyridinium; picrate 
• 110377-09-8 1-(3,4-dimethoxy-phenethyl)-4-(2-methyl-[1,3]dioxolan-2-yl)-pyridinium; bromide 
• 16552-70-8 2-<β-(3,4-Dimethoxy-phenyl)-ethyl>-6,7-dimethoxy-3,4-dihydro-isochinoliniumbromid 
• 112554-90-2 4-diethoxymethyl-1-(3,4-dimethoxy-phenethyl)-pyridinium; bromide 
• 21610-38-8 Diethyl <2-(3,4-dimethoxyphenyl)ethyl>malonate 
• 103156-63-4 (3,4-dimethoxy-phenethyl)-veratryl-malonic acid diethyl ester 
• 47609-29-0 1-(3,4-dimethoxy-phenethyl)-4-phenyl-piperidine-4-carboxylic acid ethyl ester 
• 135-89-7 1,2-Dimethoxy-4-(2-hydrazino-ethyl)-benzol 

Relevant articles and documents

CuI-catalyzed coupling of gem-dibromovinylanilides and sulfonamides: An efficient method for the synthesis of 2-amidoindoles and indolo[1,2-a] quinazolines

A Cu(I)-catalyzed, intermolecular protocol for the synthesis of 2-amidoindoles and tetrahydroindolo[1,2-a]quinazolines in shorter time and high yields is reported. The key highlight of this disclosure is the formation of 2-amidoindole and tetrahydroindolo[1,2-a]quinazoline moieties directly from gem-dibromovinylanilides and sulfonamides in a one-pot fashion through the in situ formation of ynamides followed by a base-promoted intramolecular hydroamidation.

Derivatives of cyclic ethers and sulfides for the treatment of atherosclerosis

The present invention provides compounds of Formula I, STR1 or a pharmaceutically acceptable salt forms thereof, which are inhibitors of acyl-Coenzyme A: cholesterol O-acyltransferase (ACAT), pharmaceutical compositions containing such compounds, processes for the preparation of such compounds, and the use of such compounds as antihypercholesterolemic and/or antiatherosclerotic agents.

Alpha-(phenylalkyl) pyridinealkanol derivatives

This invention relates to novel α-(phenylalkyl) pyridinealkanol derivatives useful in the treatment of diseases or disorders mediated by platelet-activating factor. This invention further relates to pharmaceutical compositions of such α-(phenylalkyl)pyridinealkanol derivatives.