40257-02-1 Usage
Description
(3-nitrophenoxy)acetyl chloride, also known as 3-nitrophenoxyacetyl chloride, is a colorless to pale yellow liquid chemical compound with a strong, pungent odor. It is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals and is known for its reactivity and high corrosiveness, which poses significant risks to human health if not handled properly.
Uses
Used in Pharmaceutical Industry:
(3-nitrophenoxy)acetyl chloride is used as a chemical intermediate for the synthesis of various pharmaceuticals. Its reactivity allows for the production of a wide range of drug compounds, contributing to the development of new medications and therapies.
Used in Agrochemical Industry:
(3-nitrophenoxy)acetyl chloride is used as a chemical intermediate in the synthesis of agrochemicals. It plays a crucial role in the production of various agricultural chemicals, such as pesticides and herbicides, which are essential for maintaining crop health and productivity.
Used in Research and Development:
(3-nitrophenoxy)acetyl chloride is utilized in research and development activities, where its reactivity is harnessed to explore new chemical reactions and synthesize novel compounds. This contributes to the advancement of scientific knowledge and the discovery of new applications in various fields.
Safety Measures:
Due to the reactivity and potential hazards of (3-nitrophenoxy)acetyl chloride, appropriate safety measures and protective equipment must be used when handling this compound. This includes wearing personal protective equipment, such as gloves, goggles, and respirators, and following proper handling and storage procedures to minimize risks to human health and the environment.
Check Digit Verification of cas no
The CAS Registry Mumber 40257-02-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,2,5 and 7 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 40257-02:
(7*4)+(6*0)+(5*2)+(4*5)+(3*7)+(2*0)+(1*2)=81
81 % 10 = 1
So 40257-02-1 is a valid CAS Registry Number.
InChI:InChI=1/C8H6ClNO4/c9-8(11)5-14-7-3-1-2-6(4-7)10(12)13/h1-4H,5H2
40257-02-1Relevant articles and documents
ADHESIVE FORMULATIONS
-
Page/Page column 12, (2010/08/22)
The disclosure relates to biocompatible components useful for forming compositions for use as medical/surgical synthetic adhesives and sealants. Biocompatible components of the present disclosure may include a polymeric polyol core, which may be treated with a nitroaryl compound to form a nitro ester. The resulting nitro ester groups may be reduced to form amino groups which, in turn, may be treated to form isocyanate groups. The resulting isocyanate may then be reacted with a second component to form adhesive and/or sealant compositions.
A convenient preparation of N-alkyl and N-arylamines by smiles rearrangement - Synthesis of analogues of diclofenac
Wadia,Patil
, p. 2725 - 2736 (2007/10/03)
Smiles rearrangement of substituted aryloxyacetamides in which oxygen and nitrogen are separated by COCH2 group has been successful even when the aryloxy ring carries weak or no electron withdrawing group. Earlier reports of such reactions involved either strong electron withdrawing groups or a special catalyst. The diphenylamines thus obtained gave analogues of diclofenac in only one case.
Synthesis of phenoxyacetic acid derivatives as highly potent antagonists of gastrin/cholecystokinin-B receptors
Takeda, Yasuyuki,Kawagoe, Keiichi,Yokomizo, Aki,Yokomizo, Yoshihiro,Hosokami, Toru,Ogihara, Yoshiyasu,Honda, Yuko,Yokohama, Shuichi
, p. 434 - 444 (2007/10/03)
A novel series of phenoxyacetic acid derivatives was synthesized based on considerations of the three-dimensional structural similarity of YM022 and RP72540. The gastrin/cholecystokinin (CCK)-B and CCK-A receptor antagonist activities of these compounds were evaluated by investigation of their affinities for human gastrin/CCK-B receptors and human CCK-A receptors, respectively. It was found that N-methyl-N-phenyl-2-[2-[N-(N-methyl-N- phenyl-carbamoylmethyl)-N-[2-[3-(3- methylphenyl)ureido]acetyl]amino]phenoxy]acetamide (20k, DZ-3514) exhibited high affinity for gastrin/CCK-B receptors and high selectivity over CCK-A receptors.