402822-68-8

Basic information

• Product Name: Phosphine oxide, [2'-(methylthio)[1,1'-biphenyl]-2-yl]diphenyl-
• CAS NO: 402822-68-8
• Molecular Formula: C25H21OPS
• Molecular Weight: 400.481
• Mol File: 402822-68-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Phosphine oxide, [2'-(methylthio)[1,1'-biphenyl]-2-yl]diphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphine oxide, [2'-(methylthio)[1,1'-biphenyl]-2-yl]diphenyl-(402822-68-8)
• EPA Substance Registry System: Phosphine oxide, [2'-(methylthio)[1,1'-biphenyl]-2-yl]diphenyl-(402822-68-8)

Safety Data

• Hazardous Substances Data: 402822-68-8(Hazardous Substances Data)

Upstream product

• 62336-24-7 (2-bromophenyl)diphenylphosphane 
• 829-85-6 diphenylphosphane 
• 4559-70-0 Diphenylphosphine oxide 
• 583-55-1 1-Bromo-2-iodobenzene 
• 88652-74-8 (2-bromophenyl)diphenylphosphine oxide 
• 168618-42-6 (2-methylsulfanylphenyl)boronic acid 

Relevant articles and documents

Palladium-catalysed synthesis of biaryl phosphines

Monodentate, biphenyl-type phosphines have emerged as a powerful class of ligands in homogeneous catalysis. Synthetic methods for these ligands are limited, however. We report that the palladium-catalysed Suzuki coupling of OPR2(o-C6H4X) (R=Ph, t-Bu; X=Br, I) with arylboronic acids affords a variety of biaryl phosphine oxides including those that contain heterocycles. The corresponding phosphines are readily obtained by treatment with HSiCl3. The methodology provides an easy entry to monodentate biaryl and heterobiaryl Poverlapping logical AND signX (X=N, O, S) phosphines with diverse steric and electronic properties.