168618-42-6 Usage
Description
2-Methylthiophenylboronic acid is a white crystalline powder that serves as a versatile reagent in organic chemistry, particularly in palladium-catalyzed cross-coupling reactions. It is known for its ability to form stable intermediates and facilitate the formation of carbon-carbon bonds, making it a valuable component in the synthesis of various organic compounds.
Uses
Used in Pharmaceutical Industry:
2-Methylthiophenylboronic acid is used as a reactant for palladium-catalyzed cross-coupling reactions, which are crucial in the synthesis of complex pharmaceutical compounds. These reactions allow for the formation of new carbon-carbon bonds, enabling the creation of a wide range of therapeutic agents with diverse structures and properties.
Used in Chemical Research:
In the field of chemical research, 2-Methylthiophenylboronic acid is employed as a reactant for Suzuki-Miyaura coupling reactions. These reactions are essential for the development of new organic compounds, including potential pharmaceuticals, agrochemicals, and advanced materials. The use of this boronic acid in Suzuki reactions allows for the efficient formation of biaryl and heteroaryl compounds, which are often found in biologically active molecules.
Used in Material Science:
2-Methylthiophenylboronic acid is also utilized in material science as a building block for the synthesis of novel materials with unique properties. The cross-coupling reactions involving this reagent can lead to the formation of new polymers, dendrimers, and other complex structures with potential applications in various industries, such as electronics, energy storage, and environmental protection.
Overall, 2-Methylthiophenylboronic acid is a valuable reagent in various fields, including pharmaceuticals, chemical research, and material science, due to its role in palladium-catalyzed cross-coupling reactions and its ability to facilitate the formation of carbon-carbon bonds in the synthesis of complex organic compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 168618-42-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,8,6,1 and 8 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 168618-42:
(8*1)+(7*6)+(6*8)+(5*6)+(4*1)+(3*8)+(2*4)+(1*2)=166
166 % 10 = 6
So 168618-42-6 is a valid CAS Registry Number.
168618-42-6Relevant articles and documents
Copper-Catalyzed Monoorganylation of Trialkyl Borates with Functionalized Organozinc Pivalates
Fu, Ying,Gou, Bei-Lei,Shi, Chun-Zhao,Du, Zhengyin,Shen, Tong
, p. 4253 - 4257 (2018/09/18)
Organozinc pivalates, a recently developed air- and moisture-stable organozinc species, were found for the first time as excellent organometallic species in the monoorganylation of trialkyl borates whereby boronic acids were prepared in high yields. The significant advantage of organozinc pivalates over another previously employed organometallic reagents, e. g., organolithium reagents, Grignard reagents and organozinc halides, is that the generation of multiorganylation byproducts such as borinic acids and trialkylboranes were completely suppressed. Additionally, the in situ generated boronates could be directly arranged into Suzuki-Miyaura type cross-coupling reactions to produce biaryls in high yields.
NITROGEN CONTAINING HETEROAROMATICS AS FACTOR Xa INHIBITORS
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Page/Page column 60, (2009/10/01)
The present application describes nitrogen containing heteroaromatics and derivatives thereof of formula (I) or pharmaceutically acceptable salt or prodrug forms thereof, wherein J is N or NH and D may be C(=NH)NH2, which are useful as inhibitors of factor Xa.
5-AMIDINO-2-HYDROXYBENZENESULFONAMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND INTERMEDIATES FOR THEIR PREPARATION
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, (2008/06/13)
The present invention relates to a 5-amidino-2-hydroxybenzenesulfonamide derivative represented by the general formula: wherein R1 is a hydrogen atom or an optionally substituted lower alkyl group; R2 is a di(lower alkyl)amino group,
