404936-83-0

Basic information

• Product Name: 3(2H)-Pyridazinone, 5-acetyl-2-(methoxymethyl)-6-phenyl-
• CAS NO: 404936-83-0
• Molecular Formula: C14H14N2O3
• Molecular Weight: 258.277
• Mol File: 404936-83-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3(2H)-Pyridazinone, 5-acetyl-2-(methoxymethyl)-6-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 3(2H)-Pyridazinone, 5-acetyl-2-(methoxymethyl)-6-phenyl-(404936-83-0)
• EPA Substance Registry System: 3(2H)-Pyridazinone, 5-acetyl-2-(methoxymethyl)-6-phenyl-(404936-83-0)

Safety Data

• Hazardous Substances Data: 404936-83-0(Hazardous Substances Data)

Upstream product

• 90766-97-5 5-bromo-6-phenylpyridazin-3(2H)-one 
• 247158-79-8 5-Bromo-2-methoxymethyl-6-phenylpyridazin-3-one 
• 617693-71-7 2-methoxymethyl-6-phenyl-5-[(1'-ethoxy)vinyl]-3-pyridazinone 

Downstream Products

• 101563-72-8 6-phenyl-5(α-hydroxyethyl)-pyridazin-3(2H)-one 
• 499783-14-1 5-(1'-hydroxyethyl)-2-methoxymethyl-6-phenyl-3(2H)-pyridazinone 
• 404936-89-6 5-acetyl-6-phenyl-2,3-dihydropyridazin-3-one 

Relevant articles and documents

Pyridazines part 41: Synthesis, antiplatelet activity and SAR of 2,4,6-substituted 5-(3-oxo-3-phenylprop-1-en-1-yl)- or 5-(3-phenylprop-2-enoyl) pyridazin-3(2H)-ones

As part of the optimization process of the lead compound I a focussed library of diversely substituted pyridazin-3(2H)-ones containing a 3-oxo-3-phenylprop-1-en-1-yl or 3-phenylprop-2-enoyl fragment at position 5 has been obtained and evaluated as antipla

Pyridazines. Part 25: Efficient and selective deprotection of pharmacologically useful 2-MOM-pyridazinones using Lewis acids

An efficient and selective procedure for the cleavage of a methoxymethyl group at the 2-position in acid-sensitive pyridazinones is presented. Deprotection with Lewis acids (boron tribromide or aluminium chloride) affords 3(2H)-pyridazinones under mild co