617693-71-7Relevant articles and documents
Pyridazines part 41: Synthesis, antiplatelet activity and SAR of 2,4,6-substituted 5-(3-oxo-3-phenylprop-1-en-1-yl)- or 5-(3-phenylprop-2-enoyl) pyridazin-3(2H)-ones
Crespo, Abel,Meyers, Caroline,Coelho, Alberto,Yanez, Matilde,Fraiz, Nuria,Sotelo, Eddy,Maes, Bert U. W.,Laguna, Reyes,Cano, Ernesto,Lemiere, Guy L. F.,Ravina, Enrique
, p. 1080 - 1083 (2007/10/03)
As part of the optimization process of the lead compound I a focussed library of diversely substituted pyridazin-3(2H)-ones containing a 3-oxo-3-phenylprop-1-en-1-yl or 3-phenylprop-2-enoyl fragment at position 5 has been obtained and evaluated as antipla