406190-09-8

Basic information

• Product Name: [(2-methylphenyl)amino](oxo)acetic acid
• Synonyms: [(2-methylphenyl)amino](oxo)acetic acid;acetic acid, [(2-methylphenyl)amino]oxo-;Albb-009526;[(2-methylphenyl)amino](oxo)acetic acid(SALTDATA: FREE);2-[(2-methylphenyl)amino]-2-oxoacetic acid;2-[(2-methylphenyl)amino]-2-oxo-acetic acid;2-[(2-methylphenyl)amino]-2-oxo-ethanoic acid;2-keto-2-[(2-methylphenyl)amino]acetic acid
• CAS NO: 406190-09-8
• Molecular Formula: C₉H₉NO₃
• Molecular Weight: 179.18
• Mol File: 406190-09-8.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Density: 1.342g/cm³
• Refractive Index: 1.62
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: [(2-methylphenyl)amino](oxo)acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: [(2-methylphenyl)amino](oxo)acetic acid(406190-09-8)
• EPA Substance Registry System: [(2-methylphenyl)amino](oxo)acetic acid(406190-09-8)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 406190-09-8(Hazardous Substances Data)

Usage

General Description

[(2-Methylphenyl)amino](oxo)acetic acid, a chemical compound also known as 2-Methylphenylglycine, has a molecular formula of C9H9NO3. The compound, appearing as a white to off-white crystalline powder, features an amino group attached to an acetic acid family along with a 2-methylphenyl group. This suggests that it has properties of both amines and carboxylic acids, including the ability to form salts and esters. Its use largely revolves around scientific research, particularly within the realm of organic chemistry, and it's not commonly known for commercial or industrial applications. Like many similar compounds, precautions should be taken when handling it due to risk of skin and eye irritation.

InChI:InChI=1/C9H9NO3/c1-6-4-2-3-5-7(6)10-8(11)9(12)13/h2-5H,1H3,(H,10,11)(H,12,13)

Upstream product

• 95-92-1 oxalic acid diethyl ester 
• 95-53-4 o-toluidine 
• 64-17-5 ethanol 
• 10468-64-1 o-tolyl isocyanide 
• 53117-14-9 ethyl 2-(2-methylanilino)-2-oxo-acetate 

Downstream Products

• 120-72-9 indole 
• 3299-62-5 N,N'-bis(o-tolyl)oxamide 
• 1477-50-5 Indole-2-carboxylic acid 
• 124-38-9 carbon dioxide 
• 7732-18-5 water 
• 69796-56-1 N,N'-bis(2-dicarboxyphenyl)oxalamide 
• 1040762-92-2 C₂₂H₁₄BrClF₃N₃O₃ 
• 1338471-38-7 (S)-5-(2,6-difluorophenoxy)-3-[(2-methyl-phenylaminooxalyl)-amino]-4-oxo-pentanoic acid 
• 1354933-61-1 C₁₇H₁₄N₂O₄ 
• 13143-13-0 N-benzyl-N’-(2-methylphenyl)urea 

Relevant articles and documents

Synthesis and biological evaluation of novel oxalamido derivatives as caspase-3 inhibitors

A new series of 5-fluoro-3-[(4-substituted-phenylaminooxalyl)-amino]-4-oxo- pentanoic acid, 7a-c, 3-[(4-substitutedphenylaminooxalyl)- amino]-4-oxo-5-(2,3, 5,6-tetrafluoro-phenoxy)-pentanoic acid, 7d-h and 5-(2,6-difluoro-phenoxy)-3- [(substituted-phenylaminooxalyl)-amino]-4-oxo-pentanoic acid, 7i-p have been synthesized from N-(substituted-phenyl)- oxalamic acid, 1 and their activities have been evaluated in vitro. Compounds 7b,c and k show low micromolar inhibitory activity against caspase-3.

From isocyanides to trichloropyruvamides: Application to a new preparation of oxamide derivatives

Isocyanides react readily with trichloroacetic acid anhydride forming stable hydrates of trichloropyruvamides. These compounds are valuable intermediates for obtaining oxamides by reaction with TMSCl/NEt3 followed by addition of an amine.