40808-62-6Relevant articles and documents
-
Eiter
, p. 252 (1952)
-
An Enantio- and Diastereoselective Mannich/Pictet–Spengler Sequence To Form Spiro[piperidine-pyridoindoles] and Application to Library Synthesis
Riesco-Domínguez, Alejandra,van der Zwaluw, Nick,Blanco-Ania, Daniel,Rutjes, Floris P. J. T.
, p. 662 - 670 (2017/02/05)
A new tandem strategy based on a Mannich/Pictet–Spengler sequence has been developed and applied to the synthesis of a new small library (14 examples) of privileged compounds based on the spiro[piperidine-pyridoindole] core. The sequence proceeds by a diastereoselective Pictet–Spengler cyclization after condensation of several tryptamine derivatives with three novel piperidin-4-ones containing the fluorinated substituents F, CF3and SF5. The piperidin-4-ones were synthesized from readily available starting materials by an enantioselective multi-component organocatalytic Mannich reaction.
Synthesis of β-pyrrolalkylamines
Hamdan, Ali,Wasley, Jan W. F.
, p. 71 - 74 (2007/10/02)
-