408512-85-6

Basic information

• Product Name: 7α-[6-(N-(2-(tert-butyldimethylsilanyloxy)-ethyl)-diphenylphosphinamido)-hexan-1-yl]-estra-1,3,5(10)triene-3,17β-bis-2-tetrahydropyranyl ether
• Synonyms: 7α-[6-(N-(2-(tert-butyldimethylsilanyloxy)-ethyl)-diphenylphosphinamido)-hexan-1-yl]-estra-1,3,5(10)triene-3,17β-bis-2-tetrahydropyranyl ether
• CAS NO: 408512-85-6
• Molecular Weight: 898.292
• Mol File: 408512-85-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 7α-[6-(N-(2-(tert-butyldimethylsilanyloxy)-ethyl)-diphenylphosphinamido)-hexan-1-yl]-estra-1,3,5(10)triene-3,17β-bis-2-tetrahydropyranyl ether(CAS DataBase Reference)
• NIST Chemistry Reference: 7α-[6-(N-(2-(tert-butyldimethylsilanyloxy)-ethyl)-diphenylphosphinamido)-hexan-1-yl]-estra-1,3,5(10)triene-3,17β-bis-2-tetrahydropyranyl ether(408512-85-6)
• EPA Substance Registry System: 7α-[6-(N-(2-(tert-butyldimethylsilanyloxy)-ethyl)-diphenylphosphinamido)-hexan-1-yl]-estra-1,3,5(10)triene-3,17β-bis-2-tetrahydropyranyl ether(408512-85-6)

Safety Data

• Hazardous Substances Data: 408512-85-6(Hazardous Substances Data)

Upstream product

• 408512-82-3 3,17β-bis(2-tetrahydropyranyloxy)-7α-(5-hexen-1-yl)-estra-1,3,5(10)triene 
• 251322-01-7 3,17β-bis(2-tetrahydropyranyloxy)-7α-(5-hexen-1-yl)-estra-1,3,5(10)-triene-6-one 
• 251322-02-8 7α-(5-hexen-1-yl)estra-1,3,5(10)-triene-3,17β-diol 
• 122566-22-7 (8R,9S,13S,14S,17S)-13-Methyl-3,17-bis-(tetrahydro-pyran-2-yloxy)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-6-ol 
• 53573-82-3 3,17β-bis(2-tetrahydropyranyloxy)estra-1,3,5(10)-triene-6-one 
• 3589-91-1 3,17β-bis(2-tetrahydropyranyloxy)estra-1,3,5(10)-triene 
• 50-28-2 estradiol 
• 408512-83-4 6-((7R,13S,14S,17S)-13-methyl-3,17-bis((tetrahydro-2H-pyran-2-yl)oxy)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-7-yl)hexan-1-ol 
• 173042-73-4 2-(tert-butyldimethylsilanoxy)ethyl-diphenylphosphinamide 
• 408512-84-5 3,17β-bis(2-tetrahydropyranyloxy)-7α-(6-bromohexan-1-yl)-estra-1,3,5(10)triene 

Downstream Products

• 740809-76-1 C₆₀H₈₆N₃O₉PS 
• 740809-75-0 7α-[6-(N-(2-hydroxyethyl)-diphenylphosphinamido)-hexan-1-yl]-estra-1,3,5(10)triene-3,17β-bis-2-tetrahydropyranyl ether 

Relevant articles and documents

A rationally designed genotoxin that selectively destroys estrogen receptor-positive breast cancer cells

We describe a novel strategy to increase the selective toxicity of genotoxic compounds. The strategy involves the synthesis of bifunctional molecules capable of forming DNA adducts that have high affinity for specific proteins in target cells. It is propo