408538-29-4

Basic information

• Product Name: 3-amino-5-chloropicolinonitrile
• Synonyms: 3-amino-5-chloropicolinonitrile
• CAS NO: 408538-29-4
• Molecular Formula: C₆H₄ClN₃
• Molecular Weight: 153.56906
• Mol File: 408538-29-4.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3-amino-5-chloropicolinonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-amino-5-chloropicolinonitrile(408538-29-4)
• EPA Substance Registry System: 3-amino-5-chloropicolinonitrile(408538-29-4)

Safety Data

• Hazardous Substances Data: 408538-29-4(Hazardous Substances Data)

Usage

General Description

3-amino-5-chloropicolinonitrile is a chemical compound with the molecular formula C6H4ClN3. It is a derivative of picolinonitrile, and its structure includes a chloro group and an amino group at the 5th and 3rd positions, respectively. 3-amino-5-chloropicolinonitrile is used in the synthesis of various organic compounds and pharmaceuticals, due to its reactivity and versatility. Its properties and structure make it valuable in the production of heterocyclic and bioactive molecules. 3-amino-5-chloropicolinonitrile is an important building block in the development of new materials and compounds, with potential applications in the pharmaceutical and chemical industries.

Upstream product

• 90902-83-3 3-amino-2-bromo-5-chloropyridine 
• 75806-86-9 2-bromo-5-chloro-3-nitropyridine 
• 21427-61-2 5-chloro-3-nitropyridin-2-ol 
• 181123-11-5 5-chloro-2-cyano-3-nitropyridine 

Downstream Products

• 27330-34-3 3-amino-5-chloropicolinamide 
• 917757-12-1 4,7-dichloro-pyrido[3,2-d]pyrimidine 

Relevant articles and documents

IDENTIFICATION AND USE OF ERK5 INHIBITORS

The present invention covers heterocyclic compounds of general formula (I) in which T, U, Y, Z, R1 and R3 are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of cancer disorders, as a sole agent or in combination with other active ingredients.

HETEROARYL SULFONAMIDES AND CCR2

Compounds are provided that act as potent antagonists of the CCR2 receptor. Animal testing demonstrates that these compounds are useful for treating inflammation, a hallmark disease for CCR2. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR2-mediated diseases, and as controls in assays for the identification of CCR2 antagonists.