90902-83-3 Usage
Description
3-AMINO-2-BROMO-5-CHLOROPYRIDINE is an organic compound with the chemical formula C5H4BrClN2. It is a heterocyclic compound that features a pyridine ring with a bromine atom at the 2nd position, a chlorine atom at the 5th position, and an amino group at the 3rd position. 3-AMINO-2-BROMO-5-CHLOROPYRIDINE is known for its reactivity and is commonly used as a building block in the synthesis of various pharmaceuticals and chemical compounds.
Uses
Used in Pharmaceutical Industry:
3-AMINO-2-BROMO-5-CHLOROPYRIDINE is used as a reactant in the synthetic preparation of Chloro(chloromethyl)thiazolopyridine, which is a precursor of PC190723. PC190723 is an antibacterial cell division inhibitor, making this compound valuable in the development of new antibiotics to combat bacterial infections.
Used in Chemical Synthesis:
3-AMINO-2-BROMO-5-CHLOROPYRIDINE is used as a key intermediate in the synthesis of various chemical compounds, including pharmaceuticals, agrochemicals, and other specialty chemicals. Its unique structure allows for further functionalization and modification, making it a versatile building block in organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 90902-83-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,0,9,0 and 2 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 90902-83:
(7*9)+(6*0)+(5*9)+(4*0)+(3*2)+(2*8)+(1*3)=133
133 % 10 = 3
So 90902-83-3 is a valid CAS Registry Number.
InChI:InChI=1/C5H4BrClN2/c6-5-4(8)1-3(7)2-9-5/h1-2H,8H2
90902-83-3Relevant articles and documents
NaI/PPh3-Mediated Photochemical Reduction and Amination of Nitroarenes
Qu, Zhonghua,Chen, Xing,Zhong, Shuai,Deng, Guo-Jun,Huang, Huawen
supporting information, p. 5349 - 5353 (2021/07/21)
A mild transition-metal- and photosensitizer-free photoredox system based on the combination of NaI and PPh3 was found to enable highly selective reduction of nitroarenes. This protocol tolerates a broad range of reducible functional groups such as halogen (Cl, Br, and even I), aldehyde, ketone, carboxyl, and cyano. Moreover, the photoredox catalysis with NaI and stoichiometric PPh3 provides also an alternative entry to Cadogan-type reductive amination when o-nitrobiarenes were used.
HETEROARYL SULFONAMIDES AND CCR2
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Page/Page column 91-92, (2008/06/13)
Compounds are provided that act as potent antagonists of the CCR2 receptor. Animal testing demonstrates that these compounds are useful for treating inflammation, a hallmark disease for CCR2. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR2-mediated diseases, and as controls in assays for the identification of CCR2 antagonists.