40976-89-4

Basic information

• Product Name: 2,4,6-Triiodo-5-(methylamino)-isophthalic acid
• Synonyms: 2,4,6-Triiodo-5-(methylamino)-isophthalic acid
• CAS NO: 40976-89-4
• Molecular Formula: C₉H₆I₃NO₄
• Molecular Weight: 0
• Mol File: 40976-89-4.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 538.7°C at 760 mmHg
• Flash Point: 279.6°C
• Appearance: /
• Density: 2.861g/cm³
• Vapor Pressure: 1.95E-12mmHg at 25°C
• Refractive Index: 1.837
• CAS DataBase Reference: 2,4,6-Triiodo-5-(methylamino)-isophthalic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4,6-Triiodo-5-(methylamino)-isophthalic acid(40976-89-4)
• EPA Substance Registry System: 2,4,6-Triiodo-5-(methylamino)-isophthalic acid(40976-89-4)

Safety Data

• Hazardous Substances Data: 40976-89-4(Hazardous Substances Data)

Usage

General Description

2,4,6-Triiodo-5-(methylamino)-isophthalic acid is a chemical compound with the molecular formula C9H6I3NO4. It is a derivative of isophthalic acid, and features three iodine atoms and a methylamino group attached to the benzene ring. 2,4,6-Triiodo-5-(methylamino)-isophthalic acid is commonly used as a contrast agent in medical imaging, particularly in computed tomography (CT) scans, to enhance the visibility of internal body structures and organs. Its high iodine content makes it an effective agent for highlighting the blood vessels and enhancing the contrast of diagnostic images. Additionally, it has been studied for potential applications in targeted drug delivery and molecular imaging due to its unique chemical structure.

InChI:InChI=1/C9H6I3NO4/c1-13-7-5(11)2(8(14)15)4(10)3(6(7)12)9(16)17/h13H,1H3,(H,14,15)(H,16,17)

Upstream product

• 50-00-0 formaldehyd 
• 35453-19-1 2,4,6-triiodo-5-aminoisophthalic acid 

Downstream Products

• 76350-18-0 2,4,6-triiodo-5-(methylamino)isophthaloyl dichloride 
• 79770-24-4 IOTROLAN 

Relevant articles and documents

preparation method of contrast agent

The present invention relates to a method for producing a contrast medium with high purity and high efficiency, and since no methyl iodide and the like are used in a production process, no salt is generated or only a very small amount thereof is generated, and a high purity and high efficiency contrast medium can be produced without complicated purification and washing steps. In addition, a small amount of salt can be easily removed by washing with water.COPYRIGHT KIPO 2018

CONTRAST AGENTS

The present invention relates to a class of compounds and to diagnostic compositions containing such compounds where the compounds are iodine containing compounds. More specifically the iodine containing compounds are chemical compounds containing two linked iodinated phenyl groups of the general formula (I) and salts or optical active isomers thereof, wherein each R1 independently are the same or different and denotes a hydrogen atom or a C1 to C4 straight or branched alkyl group which is optionally substituted by 1 to 4 - OH groups; each of R2 independently are the same or different and denote a hydrogen atom or a C1 to C4 straight or branched alkyl group; each R3 independently are the same or different and denotes a hydrogen atom or a C1 to C4 straight or branched alkyl group which is optionally substituted by 1 to 4 - OH groups; each R4 independently are the same or different and denote C1 to C6 straight or branched alkyl moieties substituted by up to 6 -OH groups; and each R5 independently are the same or different and denote C1 to C6 straight or branched alkyl moieties substituted by up to 6 -OH groups; and X denotes a straight chain alkylene moiety with 3 to 10 carbon atoms, a 1,4- cyclohexylene group, or X together with the adjacent -NR1 groups forms a 1,4- piperazine group or a 4-aminopiperidine group. The invention also relates to the use of such diagnostic compositions as contrast agents in diagnostic imaging and in particular in X-ray imaging, and to contrast media containing such compounds.