40982-92-1

Basic information

• Product Name: (3aR,5R,6R,6aR)-6-Benzyloxy-5-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxole
• Synonyms: (3aR,5R,6R,6aR)-6-Benzyloxy-5-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxole
• CAS NO: 40982-92-1
• Molecular Weight: 350.412
• Mol File: 40982-92-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (3aR,5R,6R,6aR)-6-Benzyloxy-5-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxole(CAS DataBase Reference)
• NIST Chemistry Reference: (3aR,5R,6R,6aR)-6-Benzyloxy-5-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxole(40982-92-1)
• EPA Substance Registry System: (3aR,5R,6R,6aR)-6-Benzyloxy-5-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxole(40982-92-1)

Safety Data

• Hazardous Substances Data: 40982-92-1(Hazardous Substances Data)

Upstream product

• 26597-74-0 1,2:5,6-di-O-isopropylidene-β-L-talofuranose 
• 100-39-0 benzyl bromide 
• 286011-06-1 1,2:5,6-di-O-isopropylidene-α-D-galactofuranose 
• 35777-79-8 5,6-di-O-benzoyl-3-O-benzyl-1,2-O-isopropylidene-β-L-idofuranose 
• 22529-61-9 (1R)-1-((3aR,6S,6aR)-6-(benzyloxy)-2,2-dimethyltetrahydrofuro(2,3-d)(1,3)dioxol-5-yl)ethane-1,2-diol 
• 22331-19-7 3-O-benzyl-1,2-O-isopropylidene-5,6-di-O-mesyl-α-D-glucofuranose 
• 65434-49-3 3-O-benzyl-1,2-O-isopropylidene-α-D-galactofuranose 
• 77-76-9 2,2-dimethoxy-propane 

Downstream Products

• 65877-63-6 3-O-benzyl-D-glucopyranose 
• 63593-03-3 1,2-O-isopropylidene-3-O-benzyl-4-hydroxymethyl-α-D-ribofuranose 
• 405115-97-1 (R)-3-Acetoxy-4-benzyloxy-4-[(2R,4S,5R)-5-(tert-butyl-dimethyl-silanyloxy)-2-phenyl-[1,3]dioxan-4-yl]-2-diazo-butyric acid ethyl ester 
• 405115-98-2 (Z)-(R)-2-Acetoxy-4-benzyloxy-4-[(2R,4S,5R)-5-(tert-butyl-dimethyl-silanyloxy)-2-phenyl-[1,3]dioxan-4-yl]-but-2-enoic acid ethyl ester 
• 405115-96-0 (R)-4-Benzyloxy-4-[(2R,4S,5R)-5-(tert-butyl-dimethyl-silanyloxy)-2-phenyl-[1,3]dioxan-4-yl]-2-diazo-3-hydroxy-butyric acid ethyl ester 
• 405115-99-3 (R)-4-Benzyloxy-4-[(2R,4S,5R)-5-(tert-butyl-dimethyl-silanyloxy)-2-phenyl-[1,3]dioxan-4-yl]-2-hydrazono-butyric acid ethyl ester 
• 405116-00-9 (R)-4-Benzyloxy-4-[(2R,4S,5R)-5-(tert-butyl-dimethyl-silanyloxy)-2-phenyl-[1,3]dioxan-4-yl]-2-diazo-butyric acid ethyl ester 
• 405116-01-0 (R)-4-Benzyloxy-2-diazo-4-((2R,4R,5R)-5-hydroxy-2-phenyl-[1,3]dioxan-4-yl)-butyric acid ethyl ester 
• 405116-14-5 (R)-2-Benzyloxy-2-[(2R,4S,5R)-5-(tert-butyl-dimethyl-silanyloxy)-2-phenyl-[1,3]dioxan-4-yl]-ethanol 
• 405116-13-4 Benzoic acid (R)-2-benzyloxy-2-((2R,4R,5R)-5-hydroxy-2-phenyl-[1,3]dioxan-4-yl)-ethyl ester 
• 402474-66-2 (S)-Benzyloxy-[(2R,4S,5R)-5-(tert-butyl-dimethyl-silanyloxy)-2-phenyl-[1,3]dioxan-4-yl]-acetaldehyde 
• 405116-12-3 (2R,4R,5R)-4-((R)-1-Benzyloxy-2-hydroxy-ethyl)-2-phenyl-[1,3]dioxan-5-ol 
• 405116-11-2 (S)-Benzyloxy-((2R,4R,5R)-5-hydroxy-2-phenyl-[1,3]dioxan-4-yl)-acetaldehyde 

Relevant articles and documents

CYCLIC DINUCLEOTIDE COMPOUND AND USES THEREOF

Provided are a compound of formula (I), an optical isomer thereof, a pharmaceutically acceptable salt thereof, uses of said compound acting as a STING agonist.

Ortho Ester Claisen Rearrangements of Three 3-C-(Hydroxymethyl)methylene Derivatives of Hexofuranose: Stereoselective Introduction of a Quaternary Center on C-3 of D-ribo-, L-lyxo-, and D-arabino-Hexofuranoses

Ortho ester Claisen rearrangements of (E)-3-deoxy-3-C--1,2:5,6-di-O-isopropylidene-α-D-ribo-hexofuranose (3-E), -β-L-lyxo-hexafuranose (12-E), and -β-D-arabino-hexofuranose (33-E) proceeded with high stereoselectivity to provide the rearranged products 13, 15, and 34, respectively, in acceptable yields.The rearrangements of the corresponding Z isomers 3-Z, 12-Z, and 33-Z were also investigated.The stereochemistries of the newly introduced quaternary center on C-3 of compounds 13, 15, and 34 were established unambiguouosly by chemical modifications of each rearranged product.