41137-87-5

Basic information

• Product Name: Hirsutene
• Synonyms: Hirsutenone;(4E)-1,7-Bis(3,4-dihydroxyphenyl)-4-hepten-3-one
• CAS NO: 41137-87-5
• Molecular Formula: C₁₉H₂₀O₅
• Molecular Weight: 328.3591
• Mol File: 41137-87-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 622.0±55.0 °C(Predicted)
• Appearance: /
• Density: 1.313±0.06 g/cm3(Predicted)
• Storage Temp.: ?20°C
• PKA: 9.76±0.10(Predicted)
• CAS DataBase Reference: Hirsutene(CAS DataBase Reference)
• NIST Chemistry Reference: Hirsutene(41137-87-5)
• EPA Substance Registry System: Hirsutene(41137-87-5)

Safety Data

• Hazard Codes: N
• Statements: 50
• Safety Statements: 61
• RIDADR: UN 3077 9 / PGIII
• WGK Germany: 3
• Hazardous Substances Data: 41137-87-5(Hazardous Substances Data)

Usage

General Description

Hirsutene is a chemical compound found in the resin of the North American shrub, Haplopappus hispidus. It is a sesquiterpene with a unique tricyclic structure and has been shown to possess potent anti-inflammatory and antifungal properties. Hirsutene has also demonstrated significant inhibitory effects against the growth of various cancer cell lines, making it a potential candidate for cancer therapy. Additionally, it exhibits antimicrobial activity against a range of pathogens, including bacteria and fungi. The compound has drawn interest from the scientific community for its potential pharmaceutical and medicinal applications, particularly in the development of new drugs for the treatment of inflammation, infections, and cancer.

Upstream product

• 79067-88-2 (E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-4-hepten-3-one 
• 67-56-1 methanol 
• 55303-93-0 oregonin 
• 64-17-5 ethanol 
• 458-37-7 curcumin 
• 36062-05-2 hexahydrocurcumin 
• 36062-04-1 1,7-bis(4-hydroxy-3-methoxyphenyl)-heptane-3,5-dione 

Downstream Products

• 55094-76-3 (E)-1,7-Bis-(3,4-dimethoxy-phenyl)-hept-4-en-3-one 

Relevant articles and documents

New diarylheptanoids from Alnus japonica and their antioxidative activity

In the course of research on the bioactive constituents of woody plants in the Cyugoku area of Japan, a methanol extract of the leaves of Alnus japonica were found to have strong antioxidative activity. Ethyl acetate soluble and n-buthanol soluble fractio

Synthesis of gingerenone-A and hirsutenone

Gingerenone-A 5, a diarylheptenone from Zingiber officinale, has been synthesized from vanillin 1 in four steps with an overall yield of 15%. Demethylation of 5 with AlCl3 gives hirsutenone 6, a metabolite of Alnus hirsute, in 36% yield. The spectral data of 5 and 6 are in agreement with those of natural metabolites 5 and 6 and both the compounds exhibited weak antibacterial activity.