79067-88-2

Basic information

• Product Name: 4-Hepten-3-one, 1,7-bis(4-hydroxy-3-methoxyphenyl)-
• CAS NO: 79067-88-2
• Molecular Formula: C21H24O5
• Molecular Weight: 356.419
• Mol File: 79067-88-2.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 4-Hepten-3-one, 1,7-bis(4-hydroxy-3-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Hepten-3-one, 1,7-bis(4-hydroxy-3-methoxyphenyl)-(79067-88-2)
• EPA Substance Registry System: 4-Hepten-3-one, 1,7-bis(4-hydroxy-3-methoxyphenyl)-(79067-88-2)

Safety Data

• Hazardous Substances Data: 79067-88-2(Hazardous Substances Data)

Upstream product

• 36062-05-2 hexahydrocurcumin 
• 458-37-7 curcumin 
• 36062-04-1 1,7-bis(4-hydroxy-3-methoxyphenyl)-heptane-3,5-dione 
• 98885-93-9 curcumin 
• 122-48-5 4-(4-hydroxy-3-methoxyphenyl)-2-butanone 
• 80638-48-8 3-(3'-methoxy-4'-hydroxyphenyl)propionaldehyde 
• 56024-44-3 methyl 3-(4-hydroxy-3-methoxyphenyl)propanoate 
• 1135-23-5 3-(4-hydroxy-3-methoxyphenyl)propionic acid 

Downstream Products

• 685530-97-6 1,7-bis(4-hydroxy-3-methoxy-phenyl)heptan-3-one 
• 685530-96-5 1,7-bis(4-hydroxy-3-methoxyphenyl)-4,6-heptadien-3-one 
• 470466-02-5 C₂₁H₂₀O₅ 
• 1221590-24-4 C₂₁H₂₆O₅ 
• 39886-88-9 C₂₅H₂₈O₇ 
• 41137-87-5 hirsutenone 

Relevant articles and documents

First enantioselective synthesis of gingesulfonic acids and unequivocal determination of their absolute stereochemistry

Herein we report the first organocatalysed enantioselective synthesis of gingesulfonic acids and shogasulfonic acids via a mild and convenient aminothiourea-catalysed conjugate addition of bisulfite to the olefin moiety of α,β-unsaturated carbonyls - a technology previously reported by us. A series of optically active naturally occurring sulfonic acids are prepared in their natural and unnatural configurations, and their absolute configurations are unequivocally confirmed by single crystal X-ray diffractometry.

FOOD COMPOSITION FOR PREVENTING OBESITY, PHARMACEUTICAL COMPOSITION FOR TREATING OBESITY, AND ANIMAL MEDICINE FOR TREATING OBESITY, CONTAINING GINGERNONE A

Disclosed is a composition comprising gingerenone A as an active ingredient. The composition includes a food composition for preventing obesity, a pharmaceutical composition for treating obesity and a medicine for treating animal obesity. Since the composition includes gingerenone A, which inhibits expression of the important transcriptional factors C/EBPα and PPARγ, expressed upon adipocyte differentiation, as well as FAS protein expression, the composition has superior potential for obesity prevention or treatment.

Isoxazole analogs of curcuminoids with highly potent multidrug-resistant antimycobacterial activity

Curcumin (1), demethoxycurcumin (2) and bisdemethoxycurcumin (3), the curcuminoid constituents of the medicinal plant Curcuma longa L., have been structurally modified to 55 analogs and antimycobacterial activity against Mycobacterium tuberculosis has been evaluated. Among the highly active curcuminoids, the isoxazole analogs are the most active group, with mono-O-methylcurcumin isoxazole (53) being the most active compound (MIC 0.09 μg/mL). It was 1131-fold more active than curcumin (1), the parent compound, and was approximately 18 and 2-fold more active than the standard drugs kanamycin and isoniazid, respectively. Compound 53 also exhibited high activity against the multidrug-resistant M. tuberculosis clinical isolates, with the MICs of 0.195-3.125 μg/mL. The structural requirements for a curcuminoid analog to exhibit antimycobacterial activity are the presence of an isoxazole ring and two unsaturated bonds on the heptyl chain. The presence of a suitable para-alkoxyl group on the aromatic ring which is attached in close proximity to the nitrogen function of the isoxazole ring and a free para-hydroxyl group on another aromatic ring enhances the biological activity.