4115-17-7Relevant articles and documents
Synthesis of 1,4,2,5-Dithiadiazines, a New Heterocyclic System, from Aminosulphines (Thioamide S-Oxides)
Lenz, Bodo G.,Zwanenburg, Binne
, p. 1386 - 1387 (1984)
Treatment of aryl aminosulphines (thiobenzamide S-oxides) with either Et3O+BF4- or SOCl2, followed by base, leads to 1,4,2,5-dithiadiazines.
Aerobic Visible-Light Induced Intermolecular S?N Bond Construction: Synthesis of 1,2,4-Thiadiazoles from Thioamides under Photosensitizer-Free Conditions
Wang, Hui,Xie, Shihua,Zhu, Hongjun,Zhuo, Liang
, p. 3398 - 3402 (2021/06/25)
Aerobic visible-light induced intermolecular S?N bond construction has been achieved without the addition of photosensitizer, metal, or base. With this strategy, 1,2,4-thiadiazoles can be obtained from thioamides. Preliminary mechanistic investigation suggested that the excited state of thioamides undergoes a single-electron-transfer (SET) process to afford thioamidyl radicals, which can be further transformed into a 1,2,4-thiadiazole through desulfurization and oxidative cyclization. The reaction has good functional group tolerance and represents a green method for the construction of S?N bonds.
Expedient Synthesis of 1,2,4-Thiadiazoles from Primary Thioamides Using Calcium Hypochlorite in Dichlomethane
Lee, Joanne S.,Lee, Kieseung,Lee, Seok-Ki
supporting information, p. 110 - 111 (2020/02/20)
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