57626-33-2Relevant articles and documents
CF3S(O)n-Containing olefins in cyclopropanation reactions
Sokolenko, Liubov V.,Rusanov, Eduard B.,Yagupolskii, Yurii L.
, (2021)
Cyclopropanation of trifluoromethyl(sulfinyl, sulfonyl) ethylenes was achieved by utilization of α-bromo- or α,α-dibromo 1,3-dicarbonyl compounds in the presence of bases. DBU was found to be the best choice to get satisfactory yields of cyclopropanes with CF3S(O)n (n = 1, 2) groups if α-bromo-1,3-dicarbonyl compounds were used. A series of new cyclopropanes bearing trifluoromethylsulfinyl group were synthesized.
Lipophilic indole mediated chemoselective α-monobromination of 1,3-dicarbonyl compounds
Wong, Jonathan,Ke, Zhihai,Yeung, Ying-Yeung
, (2020/03/04)
A mild and efficient mono-selective bromination of 1,3-dicarbonyl compounds has been developed using lipophilic indole catalysts. Inexpensive and commercially available N-bromosuccinimide (NBS) was used as the brominating reagent. The selectivity was further enhanced when using stoichiometric amount of 3-bromoindole species. Mechanistic studies reveal that the indole catalyst has dual functions in the mono-bromination process.
A quick, mild and efficient bromination using a CFBSA/KBr system
Jiang, Pan-Pan,Yang, Xian-Jin
, p. 90031 - 90034 (2016/10/09)
Bromination is a fundamental transformation in organic chemistry and brominated compounds as building blocks are of paramount importance in organic synthesis. In our study, we have developed an efficient method of bromination by using a CFBSA/KBr system at room temperature in a short reaction time. Notably, this approach has been proven to be applicable to a range of substrates including 1,3-diketones and β-keto esters, phenols, aromatic amines and heteroarenes with good to excellent yields.