41159-07-3

Basic information

• Product Name: 2-(4-methoxyphenyl)-2-methyl-1,3-dithiolane
• CAS NO: 41159-07-3
• Molecular Formula: C₁₁H₁₄OS₂
• Molecular Weight: 226.3583
• Mol File: 41159-07-3.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 344°C at 760 mmHg
• Flash Point: 161.8°C
• Density: 1.165g/cm³
• Vapor Pressure: 0.000135mmHg at 25°C
• Refractive Index: 1.593
• CAS DataBase Reference: 2-(4-methoxyphenyl)-2-methyl-1,3-dithiolane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-methoxyphenyl)-2-methyl-1,3-dithiolane(41159-07-3)
• EPA Substance Registry System: 2-(4-methoxyphenyl)-2-methyl-1,3-dithiolane(41159-07-3)

Safety Data

• Hazardous Substances Data: 41159-07-3(Hazardous Substances Data)

Usage

Chemical Class

2-(4-methoxyphenyl)-2-methyl-1,3-dithiolane belongs to the class of dithiolanes, which are organic compounds containing a six-membered ring with two sulfur atoms and two carbon atoms.

Molecular Structure

The compound features a methyl group (CH3) and a methoxy group (OCH3) attached to the phenyl ring, which contributes to its unique properties and applications.

Aromatic Odor

2-(4-methoxyphenyl)-2-methyl-1,3-dithiolane has a pleasant and aromatic odor, making it suitable for use in the production of fragrances and flavors.

Industrial Applications

The compound is commonly used in the perfume and food industries for creating fragrances and flavors, enhancing the sensory experience of various products.

Synthesis Intermediate

2-(4-methoxyphenyl)-2-methyl-1,3-dithiolane serves as an intermediate in the synthesis of pharmaceuticals and agrochemicals, showcasing its versatility in chemical reactions and product development.

Commercial Value

Due to its distinctive odor and diverse applications, the compound is considered an important and valuable chemical in both industrial and commercial sectors.

Upstream product

• 540-63-6 ethane-1,2-dithiol 
• 100-06-1 1-(4-methoxyphenyl)ethanone 

Downstream Products

• 110598-41-9 [(E)-2-(4-Methoxy-phenyl)-propenyl]-trimethyl-silane 
• 139214-34-9 [2-(4-methoxyphenyl)allyl]trimethylsilane 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 895-37-4 4,4'-(but-2-ene-2,3-diyl)bis(methoxybenzene) 
• 1515-95-3 p-ethylanisole 
• 59176-98-6 5-(4-methoxyphenyl)-2,3-dihydro-1,4-dithiine 

Relevant articles and documents

Mild Deprotection of Dithioacetals by TMSCl/NaI Association in CH3CN

A mild process using a combination of TMSCl and NaI in acetonitrile is used to regenerate carbonyl compounds from a variety of dithiane and dithiolane derivatives. This easy to handle and inexpensive protocol is also efficient to deprotect oxygenated and mixed acetals as 1,3-dioxanes, 1,3-dioxolanes and 1,3-oxathianes quantitatively. As a possible extension of this method, it was also shown that nitrogenated substrates such as hydrazones, N-tosylhydrazones, and ketimines reacted well under these conditions to give the expected ketones in high yields. The methodology proposed herein is a good alternative to the existing methods since it does not use metals, oxidants, reducing agents, acidic or basic media, and keto-products were obtained in high to excellent yields.

Selective arylthiolane deprotection by singlet oxygen: A promising tool for sensors and prodrugs

A routine thioketal protecting group reacts rapidly and selectively with singlet oxygen to reveal ketone products in good (aryl 1,3-dithiolane) to excellent (aryl 1,3-oxathiolane) yields. Arylthiolanes are stable to biologically relevant reactive oxygen species and can be used as a light-activated gating mechanism for activating fluorescent sensors or small molecule prodrugs.

Application of BU4N+HSO4- as an ionic liquid and acid catalyst for thioacetalization of aldehydes and ketones

A variety of carbonyl containing compounds have been successfully reacted with 1,2-ethanedithiol in a thioacetylization reaction using tetrabutylammonium hydrogensulfate as a mild and efficient catalyst. Aldehydes and ketones react with good to excellent