412274-07-8

Basic information

• Product Name: Oxiranecarboxylic acid, 3-(4-fluorophenyl)-, ethyl ester
• CAS NO: 412274-07-8
• Molecular Formula: C11H11FO3
• Molecular Weight: 210.205
• Mol File: 412274-07-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Oxiranecarboxylic acid, 3-(4-fluorophenyl)-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Oxiranecarboxylic acid, 3-(4-fluorophenyl)-, ethyl ester(412274-07-8)
• EPA Substance Registry System: Oxiranecarboxylic acid, 3-(4-fluorophenyl)-, ethyl ester(412274-07-8)

Safety Data

• Hazardous Substances Data: 412274-07-8(Hazardous Substances Data)

Upstream product

• 24393-50-8 ethyl 4-fluorocinnamate 
• 459-57-4 4-fluorobenzaldehyde 
• 105-39-5 chloroacetic acid ethyl ester 
• 136265-10-6 ethyl 4-fluorocinnamate 

Downstream Products

• 1629011-25-1 (Z)-2-(4-fluorobenzylidene)-2H-imidazo[1,2-a]pyridin-3-one 
• 846067-02-5 3-azido-3-(4-fluoro-phenyl)-2-phenoxycarbonyloxy-propionic acid ethyl ester 
• 846067-00-3 3-azido-2-ethoxycarbonyloxy-3-(4-fluoro-phenyl)-propionic acid ethyl ester 
• 846067-01-4 3-ethoxycarbonylamino-3-(4-fluoro-phenyl)-2-hydroxy-propionic acid ethyl ester 
• 846066-97-5 ethyl 3-azido-3-(4-fluorophenyl)-2-hydroxypropanoate 

Relevant articles and documents

Dioxirane Chemistry. Part 15. Rate studies on Epoxidations by Dimethyldioxirane

The relative rates of epoxidation by dimethyldioxirane, (1), of a series of 4-substituted (E)-ethyl cinnamates have been studied.The data were treated with the Hammett linear free energy relationship and give ρ = - 1.53 indicating an electrophilic O-atom transfer.Second-order rate coefficients were determined for the epoxidation of (E)-ethyl cinnamate by (1) at several temperatures and the Arrhenius factors were determined, Ea = 14.1 kcal mol-1, log (A/s-1) = 7.41.

A facile Ph3P/CO2 mediated, one-pot synthesis of 2-oxazolidinones from 1, 2-azido alcohols via phosphazene and isocyanate intermediates

A facile, efficient and convenient method has been developed for the one-pot synthesis of 2-oxazolidinones from the corresponding 1, 2-azido alcohols via phosphazene and isocyanate intermediates in presence of Ph 3P/CO2 in toluene.