413597-67-8

Basic information

• Product Name: ethyl 1-<<(tert-butyloxy)carbonyl>amino>-3-hydroxycyclobutane-1-carboxylate
• CAS NO: 413597-67-8
• Molecular Weight: 259.302
• Mol File: 413597-67-8.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: ethyl 1-<<(tert-butyloxy)carbonyl>amino>-3-hydroxycyclobutane-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 1-<<(tert-butyloxy)carbonyl>amino>-3-hydroxycyclobutane-1-carboxylate(413597-67-8)
• EPA Substance Registry System: ethyl 1-<<(tert-butyloxy)carbonyl>amino>-3-hydroxycyclobutane-1-carboxylate(413597-67-8)

Safety Data

• Hazardous Substances Data: 413597-67-8(Hazardous Substances Data)

Upstream product

• 129287-91-8 ethyl 1-<<(tert-butyloxy)carbonyl>amino>-3-oxocyclobutane-1-carboxylate 
• 1035655-28-7 1-amino-3-(benzyloxy)cyclobutane-1-carboxylic acid ethyl ester 
• 191110-49-3 2-(benzyloxy)-5,7-diazaspiro[3.4]octane-6,8-dione 
• 180205-43-0 3-(benzyloxy)-1-carbethoxycyclobutane-1-carboxylic acid 
• 54166-15-3 diethyl 3-(benzyloxy)cyclobutane-1,1-dicarboxylate 
• 413597-66-7 ethyl 3-(benzyloxy)-1-<<(tert-butyloxy)carbonyl>amino>cyclobutane-1-carboxylate 

Downstream Products

• 140480-88-2 (+/-)-1-amino-3-(phosphonomethylene)cyclobutanecarboxylic acid 
• 413597-70-3 1-amino-3-(2-aminoethylthio)-cyclobutane carboxylic acid 
• 129287-91-8 ethyl 1-<<(tert-butyloxy)carbonyl>amino>-3-oxocyclobutane-1-carboxylate 

Relevant articles and documents

HYDROXAMIC ACID DERIVATIVES AS LPXC INHIBITORS FOR THE TREATMENT OF BACTERIAL INFECTIONS

This invention pertains generally to antibacterial organic compounds of Formula I as described herein, and pharmaceutical compositions containing such compounds. In certain aspects, the invention pertains to treating infections caused by Gram-negative bac

PROCESS SIMPLIFICATION FOR PRECURSOR COMPOUND

The invention relates to a process for preparation of radiopharmaceutical precursors, and in particular protected amino acid derivatives which are used as precursors for production of radiolabelled amino acids for use in in vivo imaging procedures such as positron emission tomography (PET). Particularly, the invention relates to a process for preparation of a precursor useful in the preparation of the [18F]-1-amino-3- fluorocyclobutanecarboxyiic acid ([18F] FACBC) PET tracer.

PREPARATION OF PET PRECURSOR

The invention relates to a process for preparation of radiopharmaceutical precursors, and in particular protected amino acid derivatives which are used as precursors for production of radio labelled amino acids for use in in vivo imaging procedures such as positron emission tomography (PET). Particularly, the invention relates to a process for preparation of a precursor of the [18F]-l-amino-3-fluorocyclobutanecarboxylic acid ([18F] FACBC) PET agent, wherein a hydrogenolysis is performed using a non-gaseous hydrogen source.