4149-00-2

Basic information

• Product Name: benzimidazo[2,1-b]quinazolin-12(6H)-one
• CAS NO: 4149-00-2
• Molecular Formula: C₁₄H₉N₃O
• Molecular Weight: 235.2408
• Mol File: 4149-00-2.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 441.4°C at 760 mmHg
• Flash Point: 220.7°C
• Density: 1.45g/cm³
• Vapor Pressure: 5.47E-08mmHg at 25°C
• Refractive Index: 1.78
• CAS DataBase Reference: benzimidazo[2,1-b]quinazolin-12(6H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: benzimidazo[2,1-b]quinazolin-12(6H)-one(4149-00-2)
• EPA Substance Registry System: benzimidazo[2,1-b]quinazolin-12(6H)-one(4149-00-2)

Safety Data

• Hazardous Substances Data: 4149-00-2(Hazardous Substances Data)

Upstream product

• 118-48-9 isatoic anhydride 
• 95-54-5 1,2-diamino-benzene 
• 463-71-8 thiophosgene 
• 54255-86-6 N-<2-aminobenzoil>-o-fenilendiamina 
• 109287-33-4 trans-3-(2-nitrophenyl)oxirane-2-carboxamide 
• 51679-86-8 2-(2-amino-2-oxoacetamido)benzoic acid 
• 552-89-6 2-nitro-benzaldehyde 
• 88-74-4 2-nitro-aniline 

Downstream Products

• 116121-27-8 10-Benzyl-10H-4b,10,11-triaza-benzo[b]fluoren-5-one 
• 32700-97-3 6-Ethyl-benzimidazo<1,2-b>chinazolin-12(6H)-on 
• 32701-00-1 5-benzylbenzimidazo[2,1-b]quinazolin-12(5H)-one 
• 32701-08-9 6-(2-oxo-2-phenyl-ethyl)-6H-benzo[4,5]imidazo[2,1-b]quinazolin-12-one 

Relevant articles and documents

New and efficient synthesis of 3-arylquinazolin-4(1H)-ones and biologically important N-fused tetracycles based on N-(2-carboxyphenyl)oxalamide

A novel clean, one-pot syntheses of 3-arylquinazolin-4(3H)-ones and quinoxalino[2,1-b]quinazoline-6,12(5H)-diones via PPA-mediated coupling of N-(2-carboxyphenyl)oxalamides with arylamines and 1,2-benzenediamines have been developed. Under mild reaction conditions with use of Na2S2O4 the benzimidazo[2,1-b]quinazolin-12-ones were achieved in good yield from 3-(2-nitrophenyl)quinazolin-4-ones.

Reaction of isatoic anhydride with bifunctional reagents: Synthesis of some new quinazolone fused heterocycles, 2-substituted anilinoheterocyclic derivatives and other related compounds

A new synthesis of quinazolone fused heterocycles (2, 5, 8), anilinoheterocycles (4, 7, 10, 12, 14) and substituted 2-aminoquinoline (15, 16) based on the reaction of isatoic anhydride (1) with different active bifunctional compounds in presence of glacial acetic acid and freshly fused sodium acetate is described. Structures of the newly prepared compounds are established by chemical and spectral data.