4186-67-8 Usage
General Description
Triethylpropylammonium iodide is a chemical compound with the formula C12H28IN. It is a quaternary ammonium salt that has been used in various applications, including in the field of organic synthesis as a phase-transfer catalyst. It is a white crystalline solid that is soluble in polar organic solvents such as alcohol and acetone. Triethylpropylammonium iodide is known for its ability to facilitate the transfer of ions or molecules between immiscible phases, making it a valuable tool in chemical reactions that involve the transfer of reactants or products between different solvents. Its use as a phase-transfer catalyst can improve reaction efficiency and selectivity, making it a valuable tool in organic synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 4186-67-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,1,8 and 6 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 4186-67:
(6*4)+(5*1)+(4*8)+(3*6)+(2*6)+(1*7)=98
98 % 10 = 8
So 4186-67-8 is a valid CAS Registry Number.
InChI:InChI=1/C9H22N.HI/c1-5-9-10(6-2,7-3)8-4;/h5-9H2,1-4H3;1H/q+1;/p-1
4186-67-8Relevant articles and documents
Quaternary ammonium ions can externally block voltage-gated K+ channels. Establishing a theoretical and experimental model that predicts KDS and the selectivity of K+ over Na+ ions
Wempe
, p. 63 - 78 (2007/10/03)
The physicochemical basis for the high ion selectivity of potassium channels is poorly understood. In the present studies, external blockade of cloned voltage-gated potassium channels with alkyl quaternary ammonium ions are analyzed from a model derived from theory and experimental data. Atomic mass units, electrostatic potential residing on the nitrogen atom, the COSMO van der Waals solvent accessible surface, the Onsager solvation model, and the isodensity PCM solvation model are computed at the semi-empirical and the ab initio levels of theory. A structure-activity relationship (SAR) exists between the calculated values and the experimentally obtained KD (mM). The SAR model gives us KD predictions and when K+ and Na+ are incorporated into the model, it dramatically predicts the selectivity of K+ over Na+ ions.
