420786-27-2Relevant articles and documents
3,4-Dihydro-2H-benzoxazinones are 5-HT1A receptor antagonists with potent 5-HT reuptake inhibitory activity
Atkinson, Peter J.,Bromidge, Steven M.,Duxon, Mark S.,Gaster, Laramie M.,Hadley, Michael S.,Hammond, Beverley,Johnson, Christopher N.,Middlemiss, Derek N.,North, Stephanie E.,Price, Gary W.,Rami, Harshad K.,Riley, Graham J.,Scott, Claire M.,Shaw, Tracey E.,Starr, Kathryn R.,Stemp, Geoffrey,Thewlis, Kevin M.,Thomas, David R.,Thompson, Mervyn,Vong, Antonio K.K.,Watson, Jeannette M.
, p. 737 - 741 (2007/10/03)
Starting from a high throughput screening hit, a series of 3,4-dihydro-2H-benzoxazinones has been identified with both high affinity for the 5-HT1A receptor and potent 5-HT reuptake inhibitory activity. The 5-(2-methyl)quinolinyloxy derivative
