42084-97-9Relevant articles and documents
On the Mechanism of Propynyloxirane Rearrangement
Abdullaev, T. Kh.,Fayzilov, I. U.,Isobaev, M. D.,Jumaeva, M. I.
, p. 1853 - 1860 (2021/12/22)
Abstract: The most probable mechanism for the opening of the oxirane ring in propynyloxirane (3-ethynyl-1,2-epoxypropane) is presented. Due to the rearrangement, a mixture of the Z and E isomers of enyne alcohols is formed. The 1H NMR data and quantum-chemical calculations revealed intramolecular interactions between the π-electrons of the triple bond and the OH proton in the six-membered ring of the Z isomer.
Toward the total synthesis of disorazole A1: Asymmetric synthesis of the masked northern half
Hartung, Ingo V.,Eggert, Ulrike,Haustedt, Lars Ole,Niess, Barbara,Schaefer, Peter M.,Hoffmann, H. Martin R.
, p. 1844 - 1850 (2007/10/03)
The stereoselective synthesis of the masked northern half of the antimitotic natural product disorazole A1 is described involving as key step a Z-selective Wittig olefination of a C1-C11 epoxy aldehyde with a C12-C19 phosphonium iodide.
General methodology for the synthesis of neocarzinostatin chromophore analogues: Intramolecular chromium-mediated closures for strained-ring synthesis
Wender, Paul A.,McKinney, Jeffrey A.,Mukai, Chisato
, p. 5369 - 5370 (2007/10/02)
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