42122-75-8

Basic information

• Product Name: Methyl-5-amino-2-chlorobenzoate
• Synonyms: Methyl-5-amino-2-chlorobenzoate;BENZOIC ACID, 5-AMINO-2-CHLORO-, METHYL ESTER;METHYL 2-CHLORO-5-AMINOBENZOATE;OTAVA-BB 7020693933;TIMTEC-BB SBB013130;methyl 5-amino-2-chlorobenzoate(SALTDATA: HCl);2-Chloro-5-aMinobenzoic acid Methyl ester;5-Amino-2-chlorobenzoic acid methyl ester
• CAS NO: 42122-75-8
• Molecular Formula: C₈H₈ClNO₂
• Molecular Weight: 185.60762
• Mol File: 42122-75-8.mol
• Article Data: 23

Chemical Properties

• Melting Point: 68-70℃
• Boiling Point: 320℃
• Flash Point: 147℃
• Appearance: /
• Density: 1.311
• Vapor Pressure: 0.000333mmHg at 25°C
• Refractive Index: 1.58
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• Solubility: soluble in Methanol
• PKA: 2.81±0.10(Predicted)
• CAS DataBase Reference: Methyl-5-amino-2-chlorobenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl-5-amino-2-chlorobenzoate(42122-75-8)
• EPA Substance Registry System: Methyl-5-amino-2-chlorobenzoate(42122-75-8)

Safety Data

• Hazardous Substances Data: 42122-75-8(Hazardous Substances Data)

Usage

Chemical Properties

Pale yellow crystal

Uses

Methyl 5-amino-2-chlorobenzoate

InChI:InChI=1/C8H8ClNO2/c1-12-8(11)6-4-5(10)2-3-7(6)9/h2-4H,10H2,1H3

Upstream product

• 6307-82-0 2-chloro-5-nitro-benzoic acid methyl ester 
• 7439-89-6 iron 
• 144-55-8 sodium hydrogencarbonate 
• 67-56-1 methanol 
• 89-54-3 2-chloro-5-aminobenzoic acid 
• 1185221-13-9 C₈H₆ClN₃O₂ 
• 2516-96-3 2-chloro-5-nitrobenzoic acid 

Downstream Products

• 89951-56-4 4-chloro-5-hydroxymethyl aniline 
• 475596-72-6 methyl 2-chloro-5-[3-(2-methoxy-4-(5-phenylpentyloxy)phenyl)propanoylamino]benzoate 
• 886435-64-9 2-chloro-5-[(2-methyl-6-trifluoromethyl-pyridine-3-carbonyl)-amino]-benzoic acid methyl ester 
• 209222-45-7 1-[1-(2-toluoylmethyl)-2-oxo-5-pivaloyl-8-methyl-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-3-yl]-3-(3-methoxycarbonyl-4-chlorophenyl)urea 
• 111362-50-6 5-amino-2-chloro-benzamide 
• 937236-97-0 2-chloro-5-(5-nitro-pyridine-2-ylamino)-benzoic acid methyl ester 
• 942631-59-6 methyl 2-chloro-5-{[3-fluoro-5-(trifluoromethyl)benzoyl]amino}benzoate 
• 924859-46-1 C₈H₆Cl₂O₄S 
• 61508-36-9 4-chloro-3-methoxy-carbonylbenzenesulfonamide 
• 1172621-32-7 2-chloro-5-(6-chloro-pyrazin-2-ylamino)-benzoic acid methyl ester 
• 355368-67-1 2-chloro-5-(5-formyl-furan-2-yl)-benzoic acid methyl ester 
• 1232505-83-7 methyl 5-amino-4-bromo-2-chlorobenzoate 
• 1294496-55-1 N-(4-chloro-3-methoxycarbonyl-phenyl)-2-methyl-5-[(1-methylcyclohexylcarbonylamino)methyl]-benzamide 
• 1343457-99-7 6-chloro-3,3-dimethyl-2-(3-morpholin-4-yl-phenyl)-1,2,3,4-tetrahydro-quinoline-5-carboxylic acid 

Relevant articles and documents

The structural influence in the stability of polymer-bound diazonium salts

Various new diazonium ions on a polymeric support that have a variety of counterions and complexation with crown ethers have been prepared, and the thermal stability of these resins over a larger temperature interval has been investigated. Nonisothermal k

Synthesis and herbicidal activities of novel thiazole PPO inhibitors

Background: Protoporphyrinogen oxidase (PPO, EC 1.3.3.4) is a key enzyme in the biosynthesis of chlorophyll and heme, also the target of different types of herbicides. Thiazole compounds shown excellent biological activity, can be designed by using active groups docking for new PPO inhibitors. Objective: The objective of this study was to synthsize a series of aryl thiazole compounds as PPO inhibitors. Methods: In this study, a series of aryl thiazole compounds derivatives 11a-l were obtained from 2-chloro-5-nitrobenzoic acid as the starting material via esterification, Iron powder reduction, diazoti-zation, Hantzsch reaction and final acylation. All synthesized compounds have been tested for their herbicidal activities as a PPO inhibitors. Results: The Petri dish test indicated that all compounds exhibited good herbicidal activities at 200 mg/L using culture dish. And the post-emergence tests showed that at 150g.ai/ha on weed stem leaf spray treatment, some of the title compounds exhibited 80% inhibition rate against the dicotyle-donou weeds Amaranthus retroflexus and Eclipta prostrate. Conclusion: Good activity was noted for some compounds that compounds 11a, 11b, 11c, 11g, 11h had 80% inhibition on stems and leaves of Amaranthus retroflexus at 150g.ai/ha.

Aryl bithiazole compound and application

The invention discloses an aryl bithiazole compound and application. A series of aryl bithiazole compounds are prepared in the invention, and application of the compounds is researched. According to biological activity test results, the aryl bithiazole compound provided by the invention has excellent herbicidal activity, has wide herbicide controlling spectrum to wheat, sorghum, barnyard grass, cucumber, oilseed rapes and radish, has a high inhibition rate on broadleaf weeds, and particularly has obvious inhibitory effects on amaranthus retroflexus and eclipta prostrate.