4223-84-1 Usage
Description
1-(2-HYDROXY-5-METHOXY-4-METHYL-PHENYL)-ETHANONE is an organic compound with the molecular formula C10H12O3. It is characterized by its unique structure, which includes a phenyl ring with hydroxy, methoxy, and methyl substituents, as well as a carbonyl group attached to the ethanone moiety. 1-(2-HYDROXY-5-METHOXY-4-METHYL-PHENYL)-ETHANONE is known for its distinct chemical properties and potential applications in various industries.
Uses
Used in the Fragrance Industry:
1-(2-HYDROXY-5-METHOXY-4-METHYL-PHENYL)-ETHANONE is used as a volatile component in the Polypodiacea plant oil, which is a significant source of fragrances and scents. Its unique aroma profile contributes to the overall scent of the oil, making it a valuable addition to the fragrance industry.
Used in the Pharmaceutical Industry:
As an intermediate in the synthesis of flavanoid derivatives, 1-(2-HYDROXY-5-METHOXY-4-METHYL-PHENYL)-ETHANONE plays a crucial role in the development of new pharmaceutical compounds. Flavanoids are a class of natural compounds with diverse biological activities, including antioxidant, anti-inflammatory, and anticancer properties. By serving as a key intermediate, this compound enables the synthesis of novel flavanoid-based drugs with potential therapeutic applications.
Preparation
Obtained by reaction of acetyl chloride on 2,5-dimethoxy-4-isopropyltoluene with aluminium chloride in boiling carbon disulfide (14%).
Check Digit Verification of cas no
The CAS Registry Mumber 4223-84-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,2,2 and 3 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 4223-84:
(6*4)+(5*2)+(4*2)+(3*3)+(2*8)+(1*4)=71
71 % 10 = 1
So 4223-84-1 is a valid CAS Registry Number.
InChI:InChI=1/C10H12O3/c1-6-4-9(12)8(7(2)11)5-10(6)13-3/h4-5,12H,1-3H3
4223-84-1Relevant articles and documents
Stereoselective synthesis of Heliannuol G
Sarkar, Debayan,Ghosh, Manoj Kumar
, p. 4336 - 4339 (2017/10/18)
The first stereoselective synthesis of Heliannuol G has been achieved employing an o-quinone methide intermediate. The present synthesis triumphs over all the drawbacks associated with the reported one and reveals an impressive overall yield of 12.37%.
Synthesis of coruscanones A and B, metabolites of piper coruscans, and related compounds
Shestak,Novikov
experimental part, p. 81 - 90 (2011/01/10)
Base-catalyzed rearrangements of both individual 4-(acylmethylidene) butenolides and their mixtures prepared by condensation of citraconic anhydride with various phosphoranes occur successfully only in the presence of 5.2% MeONa in MeOH (molar ratio MeONa
Synthesis of O-methyl epi-heliannuol E
Sabui, Subir Kumar,Venkateswaran, Ramanathapuram V.
, p. 8375 - 8381 (2007/10/03)
A synthesis of the methyl ether of an epimer of the alleochemical heliannuol E is described. The route involves indium mediated allylation of a benzopyranone carboxylate and subsequent one carbon degradation to a vinyl group.
