42876-07-3

Basic information

• Product Name: 2-(2-Amino-phenoxy)-ethanol
• Synonyms: 2-(2-Amino-phenoxy)-ethanol;Ethanol, 2-(2-aminophenoxy)-
• CAS NO: 42876-07-3
• Molecular Formula: C₈H₁₁NO₂
• Molecular Weight: 153.18
• Mol File: 42876-07-3.mol
• Article Data: 13

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(2-Amino-phenoxy)-ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-Amino-phenoxy)-ethanol(42876-07-3)
• EPA Substance Registry System: 2-(2-Amino-phenoxy)-ethanol(42876-07-3)

Safety Data

• Hazardous Substances Data: 42876-07-3(Hazardous Substances Data)

Usage

General Description

2-(2-Amino-phenoxy)-ethanol, also known as Aminoethoxyphenol, is a chemical compound with the molecular formula C8H11NO2. It is commonly used as a raw material in the production of pharmaceuticals, insecticides, and dyes. It is an amino alcohol that has a phenolic structure and is soluble in water. The compound has been found to have antioxidant properties and is being studied for its potential use in various medicinal applications. However, it is also important to use caution when handling this chemical, as it can be harmful if ingested, inhaled, or comes into contact with the skin.

Upstream product

• 176324-78-0 1-[2-(2-Iodo-ethoxy)-ethoxy]-2-nitro-benzene 
• 7647-01-0 hydrogenchloride 
• 16365-25-6 2-(2-hydroxyethoxy)nitrobenzene 
• 88-75-5 2-hydroxynitrobenzene 
• 18800-37-8 1-(2-bromoethoxy)-2-nitrobenzene 
• 824-39-5 sodium o-nitrophenate 
• 1493-27-2 ortho-nitrofluorobenzene 
• 122-99-6 2-Phenoxyethanol 

Downstream Products

• 128643-13-0 2-(2-acetylaminophenoxy)ethanol 
• 850895-67-9 2-(2-acetylaminophenoxy)-1-mesyloxyethane 
• 850895-68-0 2-(2-acetylaminophenoxy)-1-dibenzylaminoethane 
• 919293-43-9 C₈H₉N₂O₂⁽¹⁺⁾*Cl^(1-) 
• 1236207-45-6 4-((3-(2-hydroxyethoxy)-4-amino)phenylazo)nitrobenzene 
• 592551-93-4 C₂₄H₂₆FN₃O₃ 
• 592552-25-5 C₃₀H₄₀FN₃O₃Si 
• 5735-53-5 1,4-benzoxazine 

Relevant articles and documents

Copper nanoparticles (CuNPs) catalyzed chemoselective reduction of nitroarenes in aqueous medium

Abstract: A procedure for practical synthesis of CuNPs from CuSO4·5H2O is established, under appropriate reaction conditions, using rice (Oryza sativa) as an economic source of reducing as well as a stabilizing agent. Optical and microscopic techniques are employed for the characterization of the synthesized CuNPs and the sizes of the particles were found to be in the range of 8 ± 2 nm. The nanoparticles are used as a catalyst for chemoselective reduction of aromatic nitro compounds to corresponding amines under ambient conditions and water as a reaction medium. Graphic abstract: CuNPs are synthesized using hydrolysed rice and used as catalyst for chemoselective reduction of nitroarenes to their corresponding amines in water. [Figure not available: see fulltext.]

Compound or pharmaceutically acceptable salt thereof, and application thereof

The invention provides a compound having a formula I or a pharmaceutically acceptable salt thereof, and a preparation method thereof. The invention also provides application of the compound having theformula I or the pharmaceutically acceptable salt there

Synthesis and characterization of selected 4,4′-diaminoalkoxyazobenzenes

The role of the -N(CH2CH2OH)2 group in producing a mutagenic response from 4-((3-(2-hydroxyethoxy)4-amino)phenylazo)-N,N-bis(2-hydroxyethyl)aniline has been investigated. To accomplish this goal, a group of substituted 4,4′-diaminoazobenzene dyes was synthesized, and their structures were confirmed using 1H NMR, TOF-LC-ESI mass spectrometry, and combustion analysis. Mutagenicity was determined using the standard Ames test in Salmonella strains TA98, TA100, and TA1538 with and without S9 enzyme activation. The results of this study provide evidence that the mutagenicity of the parent dye arises from the metabolic cleavage of N-hydroxyethyl groups to give the corresponding -NHCH2CH2OH and -NH2 substituted monoazo dyes as direct-acting mutagens. All 5 of the dyes studied were mutagenic at various levels with and without S9 enzyme activation in TA1538. In addition, the results show that removing one N-hydroxyethyl group and capping both -OH groups in the parent dye did not affect mutagenicity, whereas removing both N-hydroxyethyl groups produced a strong direct-acting mutagen in all three bacterial strains. Increasing the length of the N-alkyl chain from two to three carbon atoms eliminated mutagenicity in TA98 without S9 activation.