43002-22-8 Usage
General Description
3,5-Dichloro-2-hydroxybenzaldehyde hydrazone is a chemical compound with the molecular formula C7H6Cl2N2O. It is a hydrazone derivative of benzaldehyde, and its structure features two chlorine atoms, a hydroxyl group, and a hydrazone functionality. It is commonly used in organic synthesis as a reagent for the detection and determination of metal ions, particularly copper, due to its ability to form colored complexes with metal ions. Additionally, it has been studied for its potential biological activities, including its antimicrobial, antifungal, and anti-inflammatory properties.
Check Digit Verification of cas no
The CAS Registry Mumber 43002-22-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,3,0,0 and 2 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 43002-22:
(7*4)+(6*3)+(5*0)+(4*0)+(3*2)+(2*2)+(1*2)=58
58 % 10 = 8
So 43002-22-8 is a valid CAS Registry Number.
InChI:InChI=1/C7H6Cl2N2O/c8-5-1-4(3-11-10)7(12)6(9)2-5/h1-3,12H,10H2/b11-3+
43002-22-8Relevant articles and documents
Synthesis and antifungal activity of substituted salicylaldehyde hydrazones, hydrazides and sulfohydrazides
Backes, Gregory L.,Neumann, Donna M.,Jursic, Branko S.
, p. 4629 - 4636 (2014/11/08)
Efficient synthetic procedures for the preparation of acid hydrazines and hydrazides were developed by converting the corresponding carboxylic acid into the methyl ester catalyzed by Amberlyst-15, followed by a reaction with hydrazine monohydrate. Sulfohydrazides were prepared from the corresponding sulfonyl chlorides and hydrazine monohydrate. Both of these group of compounds were condensed with substituted salicylaldehydes using gradient concentration methods that generated a large library of hydrazone, hydrazide and sulfohydrazide analogs. Antifungal activity of the prepared analogs showed that salicylaldehyde hydrazones and hydrazides are potent inhibitors of fungal growth with little to no mammalian cell toxicity, making these analogs promising new targets for future therapeutic development.
