430461-53-3Relevant articles and documents
Diastereoselective arylation of enantiopure 3-bromopiperidin-2-one derived from (R)-(-)-2-phenylglycinol with organocuprate reagents
Romero, Oscar,Castro, Alejandro,Terán, Joel L.,Gnecco, Dino,Orea, María L.,Mendoza, ángel,Flores, Marcos,Roa, Luis F.,Juárez, Jorge R.
, p. 5947 - 5950 (2011/11/29)
The diastereoselective substitution of 3-bromolactam derived from (R)-(-)-2-phenylglycinol with a variety of arylcuprate reagents is presented. The stereochemical outcome of the substitution reaction is discussed. The method provides an efficient and stra