43047-95-6

Basic information

• Product Name: 2-phenylethyl 4-chlorobenzoate
• Synonyms: 2-Phenylethyl 4-chlorobenzoate
• CAS NO: 43047-95-6
• Molecular Formula: C₁₅H₁₃ClO₂
• Molecular Weight: 260.7155
• Mol File: 43047-95-6.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 379.7°C at 760 mmHg
• Flash Point: 195.7°C
• Density: 1.204g/cm³
• Vapor Pressure: 5.74E-06mmHg at 25°C
• Refractive Index: 1.579
• CAS DataBase Reference: 2-phenylethyl 4-chlorobenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenylethyl 4-chlorobenzoate(43047-95-6)
• EPA Substance Registry System: 2-phenylethyl 4-chlorobenzoate(43047-95-6)

Safety Data

• Hazardous Substances Data: 43047-95-6(Hazardous Substances Data)

Upstream product

• 60-12-8 2-phenylethanol 
• 18362-49-7 1,3-bis(4-chlorophenyl)propane-1,3-dione 
• 99-91-2 para-chloroacetophenone 
• 74-11-3 para-chlorobenzoic acid 
• 104-88-1 4-chlorobenzaldehyde 
• 7099-88-9 4-chlorophenylglyoxylic acid 
• 619-56-7 4-chlorobenzamide 

Relevant articles and documents

Br?nsted Acid Mediated Nucleophilic Functionalization of Amides through Stable Amide C?N Bond Cleavage; One-Step Synthesis of 2-Substituted Benzothiazoles

We have developed a Br?nsted acid mediated synthetic method to directly cleave stable amide C?N bonds by a variety of alcohol and amine nucleophiles. Reverse reactivity was observed and alcoholysis of amides by activated primary and secondary benzylic, and propargylic alcohols have been achieved instead of the expected nucleophilic substitution of alcohols. As an application, 2-substituted benzothiazole derivatives have been synthesized in one pot employing 2-aminothiophenol as nucleophile.

Efficient and selective esterification of aromatic aldehydes with alcohols (1:1) using air as the simplest available oxidant and KCN

A new and efficient method is described for the oxidative esterification of aromatic aldehydes with different types of alcohols such as primary, secondary, benzylic, allylic and cyclic alcohols and phenols using air as the simplest available oxidant and potassium cyanide in DMF under neutral conditions in high yields. The present method esterifies aldehydes with alcohols in 1:1 molar ratio with excellent chemoselectivity and avoids the use of an external oxidant beside 02 from air.

Staudinger’s phosphazene as an efficient esterifying reagent

A new application of Staudinger’s phosphazene as an efficient esterifying reagent is reported. Staudinger’s phosphazene formed in situ by the reaction of organic mono-azide with triphenylphosphine, which is trapped by carboxylic acid, to afford amide exclusively. In contrast, interestingly the same phosphazene behaves in a different way as an efficient esterifying reagent, affording ester under a solvent-free microwave-assisted protocol wherein alcohol is added as the another component in addition to the other reactants. This discovery adds yet another new application of Staudinger’s phosphazene to synthetic chemistry.