432-03-1

Basic information

• Product Name: 1,1,1-trifluoro-N,N-bis(trifluoromethyl)methanamine
• Synonyms: 1,1,1-Trifluoro-N,N-bis(trifluoromethyl)methanamine; methanamine, 1,1,1-trifluoro-N,N-bis(trifluoromethyl)-; Tris(trifluoromethyl)amine
• CAS NO: 432-03-1
• Molecular Formula: C₃F₉N
• Molecular Weight: 221.0244
• Mol File: 432-03-1.mol
• Article Data: 4

Chemical Properties

• Density: 1.643g/cm³
• Vapor Pressure: 2960mmHg at 25°C
• Refractive Index: 1.247
• CAS DataBase Reference: 1,1,1-trifluoro-N,N-bis(trifluoromethyl)methanamine(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1,1-trifluoro-N,N-bis(trifluoromethyl)methanamine(432-03-1)
• EPA Substance Registry System: 1,1,1-trifluoro-N,N-bis(trifluoromethyl)methanamine(432-03-1)

Safety Data

• Hazardous Substances Data: 432-03-1(Hazardous Substances Data)

Usage

Physical state

Colorless liquid

Odor

Pungent

Uses

a. Reagent in organic synthesis
b. Building block in the production of pharmaceuticals and agrochemicals

Reactivity

Highly reactive

Solvent properties

Strong

Environmental impact

Potent greenhouse gas with high global warming potential

Regulation

Use and production are regulated due to negative environmental impact

Safety precautions

Handle and store with care due to potential hazards

Upstream product

• 3853-06-3 methyl 3-(dimethylamino)propionate 
• 75-50-3 trimethylamine 
• 110-18-9 N,N,N,N,-tetramethylethylenediamine 
• 75-57-0 tetramethlyammonium chloride 
• 373-80-8 trifluoromethyl sulfur pentafluoride 
• 371-71-1 Perfluoro-2-azapropen 
• 1426-41-1 N,N,N',N'-Tetrafluor-1,2-diamino-1,1,2,2-tetrafluor-ethan 
• 10026-18-3 cobalt(III) fluoride 
• 428-71-7 perfluoro(2-aza-1-butene) 
• 686-39-5 tris-trifluoromethyl-carbamimidoyl fluoride 

Downstream Products

• 75-73-0 carbon tetrafluoride 

Relevant articles and documents

HEXA-, HEPTA- UND OCTAFLUORTRIMETHYLAMIN

The electrofluorination of N(CH3)3 yields, along with fragmentation and recombination products and N(CF3)3 (I), minor quantities of the hitherto unknown compounds (CF3)2NCF2H (II), CF3N(CF2H)2 (III) and N(CF2H)3 (IV).I-IV have been isolated and characterized by their (1)H, (13)C and (19)F nmr and their EI and CI mass spectra.

Electrochemical fluorination of N,N,N',N'-tetramethylethylenediamine

The electrochemical fluorination of N,N,N',N'-tetramethylethylenediamine was canied out in a modified Simons type cell using anhydrous hydrogen fluoride as a solvent. Effects of various experimental parameters like concentration of amine, temperature, and current density etc. were investigated. In addition to perfluoro-N,N,N',N'-tetramethylethylenediamine, cyclic, cleavage, and partially fluorinated products were obtained and characterized by gas chromatography, IR spectroscopy, nuclear magnetic resonance and mass spectra. A plausible reaction pathway for the electrochemical fluorination of N,N,N',N'-tetramethylethylenediamine has been proposed based on the products obtained. Elsevier Science S.A.