4350-41-8

Basic information

• Product Name: 2-(4-Chlorobenzyl)pyridine
• Synonyms: 2-(P-CHLOROBENZYL)PYRIDINE;2-(4-CHLOROBENZYL)PYRIDINE;4-CHLOROPHENYL 4-PYRIDYL KETONE;Pyridine, 2-[(4-chlorophenyl)methyl]-;2-[(4-Chlorophenyl)methyl]pyridine.;2-(4-Chlorobenzyl)pyridine,97%;2-(p-Chlorobenzy)pyridine
• CAS NO: 4350-41-8
• Molecular Formula: C₁₂H₁₀ClN
• Molecular Weight: 203.67
• EINECS: 224-412-7
• Mol File: 4350-41-8.mol
• Article Data: 17

Chemical Properties

• Melting Point: 8°C
• Boiling Point: 181-183°C (20 mmHg)
• Flash Point: >110°C
• Appearance: clear light yellow liquid
• Density: 1.39
• Vapor Pressure: 0.000951mmHg at 25°C
• Refractive Index: 1.5858-1.5878
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• PKA: 4.88±0.10(Predicted)
• BRN: 133425
• CAS DataBase Reference: 2-(4-Chlorobenzyl)pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-Chlorobenzyl)pyridine(4350-41-8)
• EPA Substance Registry System: 2-(4-Chlorobenzyl)pyridine(4350-41-8)

Safety Data

• Statements: 20/21/22
• Safety Statements: 24/25
• Hazardous Substances Data: 4350-41-8(Hazardous Substances Data)

Usage

Chemical Properties

CLEAR LIGHT YELLOW LIQUID

InChI:InChI=1/C12H10ClN/c13-11-6-4-10(5-7-11)9-12-3-1-2-8-14-12/h1-8H,9H2

Upstream product

• 110-86-1 pyridine 
• 622-95-7 4-chlorobenzyl bromide 
• 87577-90-0 2-[(1-phenylmethyl)sulfinyl]pyridine 
• 874-72-6 4-chlorobenzylmagnesium chloride 
• 26437-49-0 tris(2-pyridyl)phosphine oxide 
• 119929-94-1 2-((4-chlorobenzyl)sulfinyl)pyridine 
• 6921-34-2 benzylmagnesium chloride 
• 68469-77-2 bis(2-pyridyl)phenylphosphine-P-oxide 
• 122715-12-2 benzyldi(pyridin-2-yl)phosphine oxide 
• 122715-13-3 (4-methylbenzyl)-bis(pyridin-2-yl)phosphine oxide 
• 1201003-31-7 6-(4-chlorophenyl)hex-5-ynal oxime 
• 106-39-8 bromochlorobenzene 
• 106966-98-7 potassium 2-(pyridin-2-yl)acetate 
• 29540-84-9 4-chlorophenyl trifluoromethanesulfonate 

Downstream Products

• 107275-98-9 [3-(4-chloro-phenyl)-1-methyl-3-[2]pyridyl-propyl]-dimethyl-amine 
• 132648-56-7 1-[1-(4-chloro-phenyl)-indolizin-3-yl]-ethanone 
• 107915-11-7 1-(4-chloro-phenyl)-3-methyl-indolizine 
• 132-22-9 Chlorpheniramine 
• 55486-46-9 3-(4-chloro-phenyl)-3-[2]pyridyl-propionaldehyde-diethylacetal 
• 6318-51-0 2-(4-chlorobenzoyl)pyridine 
• 27652-89-7 (4-chlorophenyl)-2-pyridylmethanol 
• 101780-81-8 diethyl-[3-(4-chloro-phenyl)-3-[2]pyridyl-propyl]-amine 
• 76427-52-6 9-(4-Chloro-phenyl)-2-methyl-2,4,4b-triaza-phenanthrene-1,3-dione 
• 76427-54-8 9-(4-Chloro-phenyl)-2-phenyl-2,4,4b-triaza-phenanthrene-1,3-dione 
• 233760-12-8 2-[1-(4-chloro-phenyl)-2-[1,3]dioxolan-2-yl-ethyl]-pyridine 
• 55486-47-0 3-(p-chlorophenyl)-3-(2-pyridyl)propanal 
• 108984-17-4 2-[1-(4-chloro-phenyl)-3-piperidino-propyl]-pyridine 
• 6936-90-9 2-(4-chlorobenzyl)piperidine hydrochloride 

Relevant articles and documents

1/10-water maleic acid chlorpheniramine compound and pharmaceutical composition thereof (by machine translation)

The invention discloses-water 1/10 maleic acid chlorphenamine maleate compound and a preparation method thereof, wherein the compound is measured by a powder X-2 θ ± 0.2° ray diffraction method and shows characteristic 12.4 ° diffraction peaks 18.9 ° 13.1 ° at 20.3 ° 19.4 ° diffraction 21.6 ° 22.0 ° angles in 24.2 ° 24.7 °, 25.1 ° 26.3 ° and 30.1 ° 32.3 °. 1/10 Water prepared by the method has the advantages of good stability, high purity, good solubility and high bioavailability of the preparation, and is simple in process, high in yield, high in repeatability and suitable for industrial production. (by machine translation)

Ligand-Free Iridium-Catalyzed Dehydrogenative ortho C?H Borylation of Benzyl-2-Pyridines at Room Temperature

A convenient and ligand-free iridium-catalyzed dehydrogenative ortho C?H borylation of benzyl-2-pyridines has been developed. The reaction proceeds smoothly at room temperature using pinacolborane as a borylating reagent in the presence of catalytic amount of [IrOMe(COD)]2. The reaction is compatible with many functional groups, providing a vast array of ortho borylated products in moderate to excellent yields with excellent selectivities. (Figure presented.).

Cobalt-Catalyzed Formation of Functionalized Diarylmethanes from Benzylmesylates and Aryl Halides

A simple cobalt-catalyzed reductive coupling protocol allowing the synthesis of functionalized diarylmethanes from benzyl mesylate is described. The possibility to directly use the benzyl alcohol as a result of a two-step reaction is also presented. This method tolerates a variety of functional groups. A benzyl radical is likely involved. (Figure presented.).