436865-50-8

Basic information

• Product Name: N-(3-hydroperoxy-3-methyl-6-oxocyclohexa-1,4-dienyl)acetamide
• Synonyms: N-(3-hydroperoxy-3-methyl-6-oxocyclohexa-1,4-dienyl)acetamide
• CAS NO: 436865-50-8
• Molecular Weight: 197.191
• Mol File: 436865-50-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(3-hydroperoxy-3-methyl-6-oxocyclohexa-1,4-dienyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-hydroperoxy-3-methyl-6-oxocyclohexa-1,4-dienyl)acetamide(436865-50-8)
• EPA Substance Registry System: N-(3-hydroperoxy-3-methyl-6-oxocyclohexa-1,4-dienyl)acetamide(436865-50-8)

Safety Data

• Hazardous Substances Data: 436865-50-8(Hazardous Substances Data)

Upstream product

• 6375-17-3 2-acetylamino-p-cresol 

Downstream Products

• 436865-51-9 N-(3-hydroxy-3-methyl-6-oxocyclohexa-1,4-dienyl)acetamide 

Relevant articles and documents

An efficient regioselective and diastereoselective synthesis of the epoxy-quinol functionality as building block for the Manumycin antibiotics by the sequence of photooxygenation, reduction and Weitz-Scheffer epoxidation

The photooxygenation of the acetanilide 2 affords the hydroperoxide 3, which by titanium-tetraisopropoxide-catalyzed reduction with dimethyl sulfide gives the corresponding quinol 4. Regioselective and diastereoselective Weitz-Scheffer epoxidation of the latter by tert-butyl hydroperoxide (TBHP) and DBU as base catalyst leads to the cis-epoxy quinol 1, the essential functionality in Manumycin antibiotics.