439814-87-6

Basic information

• Product Name: 4-BROMO-2-FLUOROBENZALDEHYDE DIMETHYL ACETAL
• Synonyms: 4-BROMO-2-FLUOROBENZALDEHYDE DIMETHYL ACETAL;4-Bromo-1-(dimethoxymethyl)-2-fluorobenzene;-2-fluorobenzene;4-Bromo-1-(dimethoxymethyl)
• CAS NO: 439814-87-6
• Molecular Formula: C₉H₁₀BrFO₂
• Molecular Weight: 249.08
• Product Categories: Adehydes, Acetals & Ketones;Bromine Compounds;Fluorine Compounds
• Mol File: 439814-87-6.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 232.9°C at 760 mmHg
• Flash Point: 117.9°C
• Appearance: /
• Density: 1.442g/cm³
• Vapor Pressure: 0.0876mmHg at 25°C
• Refractive Index: 1.509
• CAS DataBase Reference: 4-BROMO-2-FLUOROBENZALDEHYDE DIMETHYL ACETAL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BROMO-2-FLUOROBENZALDEHYDE DIMETHYL ACETAL(439814-87-6)
• EPA Substance Registry System: 4-BROMO-2-FLUOROBENZALDEHYDE DIMETHYL ACETAL(439814-87-6)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 439814-87-6(Hazardous Substances Data)

Usage

General Description

4-Bromo-2-fluorobenzaldehyde dimethyl acetal is an organic compound with the molecular formula C10H11BrFO2. It is a colorless liquid that is commonly used as a building block in organic synthesis. This chemical is primarily used as an intermediate in the production of pharmaceuticals and agrochemicals. It can also be used as a solvent or reagent in chemical reactions. 4-Bromo-2-fluorobenzaldehyde dimethyl acetal is known for its strong aroma and is considered to be a hazardous substance that should be handled with caution and under proper safety measures.

InChI:InChI=1/C9H10BrFO2/c1-12-9(13-2)7-4-3-6(10)5-8(7)11/h3-5,9H,1-2H3

Upstream product

• 67-56-1 methanol 
• 57848-46-1 4-bromo-2-fluorobenzaldehyde 
• 497-19-8 sodium carbonate 
• 149-73-5 trimethyl orthoformate 
• 1435-52-5 2,5-dibromofluorobenzene 

Downstream Products

• 439814-88-7 4-(dimethoxymethyl)-3-fluorobenzaldehyde 
• 1445902-93-1 1-(4-(4-((cyclobutylamino)methyl)-3-fluorophenyl)piperazin-1-yl)ethanone 
• 1445901-81-4 N-(4-(4-acetylpiperazin-1-yl)-2-fluorobenzyl)-3,5-dichloro-N-cyclobutylbenzenesulfonamide 
• 1445902-92-0 4-(4-acetylpiperazin-1-yl)-2-fluorobenzaldehyde 
• 1445902-18-0 N-[4-(4-acetyl-piperazin-1-yl)-2-fluoro-benzyl]-N-cyclobutyl-benzenesulfonamide 
• 1445901-80-3 N-[4-(4-acetyl-piperazin-1-yl)-2-fluoro-benzyl]-N-cyclobutyl-1-phenylmethanesulfonamide 
• 1445901-30-3 2-phenylethanesulfonic acid N-[4-(4-acetylpiperazin-1-yl)-2-fluorobenzyl]-N-cyclobutylamide 
• 1445901-23-4 N-[4-(4-acetylpiperazin-1-yl)-2-fluorobenzyl]-N-cyclobutyl-2-fluoro-benzenesulfonamide 
• 1445901-76-7 N-[4-(4-acetyl-piperazin-1-yl)-2-fluoro-benzyl]-N-cyclobutyl-1-(2-fluorophenyl)-methanesulfonamide 
• 1445901-21-2 N-[4-(4-acetylpiperazin-1-yl)-2-fluorobenzyl]-N-cyclobutyl-3-fluoro-benzenesulfonamide 
• 1445901-74-5 N-[4-(4-acetyl-piperazin-1-yl)-2-fluoro-benzyl]-N-cyclobutyl-1-(3-fluorophenyl)-methanesulfonamide 
• 1445902-17-9 N-[4-(4-acetyl-piperazin-1-yl)-2-fluoro-benzyl]-N-cyclobutyl-4-fluoro-benzenesulfonamide 
• 1445901-75-6 N-[4-(4-acetyl-piperazin-1-yl)-2-fluoro-benzyl]-N-cyclobutyl-1-(4-fluorophenyl)-methanesulfonamide 
• 1445901-20-1 N-[4-(4-acetyl-piperazin-1-yl)-2-fluoro-benzyl]-2-chloro-N-cyclobutyl-benzenesulfonamide 

Relevant articles and documents

Synthesis and Transformations of Functionalized Benzosiloxaboroles

The synthesis and characterization of a series of fluorinated benzosiloxaboroles bearing synthetically useful formyl and cyano groups is reported. These compounds have been obtained by multistep syntheses starting with simple halogenated benzenes. The general synthetic protocol was based on the generation of ortho-boronated aryldimethylsilanes which undergo dehydrogenative cyclization upon hydrolytic workup due to activation of the Si–H bond by the adjacent boronic group. In some cases the synergy of adjacent boron- and silicon-based functionalities resulted in an unexpected hydrosilylation of the CHO group under mild aqueous conditions. The reduction of a benzosiloxaborole derivative bearing the formyl group at the ortho position with respect to the boron atom resulted in a structural transformation reflecting the higher stability of the carboxaborole heterocycle with respect to its silicon counterpart. Thus, a unique heterocyclic system featuring a central 10-membered ring comprising two borasiloxane linkages was isolated.

Therapeutic diphenyl ether ligands

This invention is directed to compounds of formula Ia, Ib or Ic and to pharmaceutical compositions thereof: or a prodrug thereof and a pharmaceutically acceptable carrier, wherein the R groups are defined in the specification; and, in which the dashed line represents an optional double bond. The invention is also directed to methods of treating, diagnosing, and preventing disorders of the central nervous system that are associated with 5HT receptors, including obesity, attention deficit disorder, migraine, depression, epilepsy, anxiety, Alzheimer's disease, withdrawal from drug abuse, pain, schizophrenia, stress-related disorders, panic disorder, sleep disorders, phobias, obsessive compulsive disorder, post-traumatic-stress syndrome, immune system depression, stress-induced gastrointestinal dysfunction, stress-induced cardiovascular dysfunction, and sexual dysfunction.