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443687-78-3

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443687-78-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 443687-78-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,4,3,6,8 and 7 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 443687-78:
(8*4)+(7*4)+(6*3)+(5*6)+(4*8)+(3*7)+(2*7)+(1*8)=183
183 % 10 = 3
So 443687-78-3 is a valid CAS Registry Number.

443687-78-3Downstream Products

443687-78-3Relevant articles and documents

Anionic cyclophanes as potential reversal agents of muscle relaxants by chemical chelation

Cameron, Kenneth S.,Fielding, Lee,Mason, Rona,Muir, Alan W.,Rees, David C.,Thorn, Simon,Zhang, Ming-Qiang

, p. 753 - 755 (2002)

A series of carboxyl-containing cyclophanes have been designed and synthesised as chemical chelators (or host molecules) of cationic muscle relaxant drugs (or guest molecules). Three of these cyclophane derivatives, 1-3, have been shown by NMR to form 1:1 complexes with the muscle relaxants pancuronium, 4 and gallamine, 5 in D2O, with association constants up to 104 M-1. When tested in an in vitro chick biventer muscle preparation, the cyclophanes reversed the neuromuscular block induced by pancuronium and gallamine, with 3 having the most effective reversal against pancuronium (EC50 40 μM).

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