445380-60-9Relevant articles and documents
Synthesis of Axially Chiral 2,2′-Bisphosphobiarenes via a Nickel-Catalyzed Asymmetric Ullmann Coupling: General Access to Privileged Chiral Ligands without Optical Resolution
Zuo, Ziqing,Kim, Raphael S.,Watson, Donald A.
, p. 1328 - 1333 (2021/02/01)
We report an asymmetric homocoupling of ortho-(iodo)arylphosphine oxides and ortho-(iodo)arylphosphonates resulting in highly enantioenriched axially chiral bisphosphine oxides and bisphosphonates. These products are readily converted to enantioenriched b
Synthesis and Molecular Modeling Studies of SYNPHOS(R), a New, Efficient Diphosphane Ligand For Ruthenium-Catalyzed Asymmetric Hydrogenation
Paule, Sebastien Duprat de,Jeulin, Severine,Ratovelomanana-Vidal, Virginie,Genet, Jean-Pierre,Champion, Nicolas,Dellis, Philippe
, p. 1931 - 1941 (2007/10/03)
A new, optically active, atropisomeric diphosphane ligand, (2,3,2',3'-tetrahydro-5,5'-bi(1,4-benzodioxin)-6,6'-diyl)bis-(diphenylphosphane) (SYNPHOS(R)), has been synthesized, characterized, and used in ruthenium-catalyzed asymmetric hydrogenations. This new ligand has been compared with other atropisomeric diphosphanes (BINAP and MeO-BIPHEP) with respect to their dihedral angles calculated by molecular modeling and the enantioselectivity of their ruthenium-mediated hydrogenation reactions.
SYNPHOS, a new chiral diphosphine ligand: Synthesis, molecular modeling and application in asymmetric hydrogenation
Duprat De Paule, Sébastien,Jeulin, Séverine,Ratovelomanana-Vidal, Virginie,Genêt, Jean-Pierre,Champion, Nicolas,Dellis, Philippe
, p. 823 - 826 (2007/10/03)
A new optically active diphosphine ligand, [(5,6),(5′,6′)-bis(ethylenedioxy)biphenyl-2,2′-diyl]bis (diphenylphosphine) (SYNPHOS) has been synthesized and used in ruthenium-catalyzed asymmetric hydrogenation. This new ligand has been compared to other diphosphines (BINAP and MeO-BIPHEP), regarding their dihedral angles and the enantioselectivity in the ruthenium mediated hydrogenation reaction.
