503269-72-5

Basic information

• Product Name: (2,3-dihydro-1,4-benzodioxin-6-yl)diphenylphosphine
• Synonyms: (2,3-dihydro-1,4-benzodioxin-6-yl)diphenylphosphine
• CAS NO: 503269-72-5
• Molecular Weight: 320.328
• Mol File: 503269-72-5.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (2,3-dihydro-1,4-benzodioxin-6-yl)diphenylphosphine(CAS DataBase Reference)
• NIST Chemistry Reference: (2,3-dihydro-1,4-benzodioxin-6-yl)diphenylphosphine(503269-72-5)
• EPA Substance Registry System: (2,3-dihydro-1,4-benzodioxin-6-yl)diphenylphosphine(503269-72-5)

Safety Data

• Hazardous Substances Data: 503269-72-5(Hazardous Substances Data)

Upstream product

• 493-09-4 benzo-1,4-dioxane 
• 1079-66-9 chloro-diphenylphosphine 
• 52287-51-1 6-bromo-1,4-benzodioxane 

Downstream Products

• 503538-68-9 (S)-[(5,6),(5’,6’)-bis(ethylenedioxy)biphenyl-2,2’ diyl]bis(diphenylphosphine) 
• 503538-67-8 [2,3,2',3'-tetrahydro-5,5'-bi(1,4-benzodioxin)-6,6'-diyl]bis-(diphenylphosphane oxide) 
• 445380-61-0 (5-iodo-2,3-dihydro-1,4-benzodioxin-6-yl)diphenylphospane oxide 
• 445380-60-9 (2,3-dihydro-1,4-benzodioxin-6-yl)phospane oxide 

Relevant articles and documents

Synthesis of new chiral diphosphine ligand (BisbenzodioxanPhos) and its application in asymmetric catalytic hydrogenation

The new chiral diphosphine ligand [(5,6), (5′,6′)-bis(1,2-ethylenedioxy)biphenyl-2,2′-diyl]bis (diphenylphosphine) (BisbenzodioxanPhos) has been successfully prepared and used in ruthenium-catalyzed asymmetric hydrogenation of 2-(6′-methoxy-2′-naphthyl)propenoic acid and β-keto esters with high enantioselectivity (92.2% and up to 99.5% ee, respectively).

Novel diphosphines, their complexes with transisition metals and their use in asymmetric synthesis

The invention relates to novel diphosphines, in optically pure or racemic form, of formula (I): in which: R1 and R2 are a (C5-C7)cycloalkyl group, an optionally substituted phenyl group or a 5-membered heteroaryl group; and A is (CH2—CH2) or CF2. The invention further relates to the use of a compound of formula (I) as a ligand for the preparation of a metal complex useful as a chiral catalyst in asymmetric catalysis, and to the chiral metal catalysts comprising at least one ligand of formula (I).

SYNPHOS: A new atropisomeric diphosphine ligand. From laboratory-scale synthesis to scale-up development

A new optically active diphosphine ligand, [(5,6),(5′,6′)-bis(ethylenedioxy)biphenyl.2,2′-diyl]bis (diphenylphosphine) (SYNPHOS) has been synthesized. Laboratory-scale synthesis and scale-up development of this ligand are described herein. This new atropisomeric diphosphine was also used in ruthenium-catalyzed asymmetric hydrogenation.