446880-80-4 Usage
Structure
Consists of a pyridine ring with a bromine substituent at the 2-position and a methyl substituent at the 6-position, and an ethanone group attached to the nitrogen atom of the pyridine ring.
Type of compound
Ethanone derivative
Usage
Commonly used in organic synthesis as a building block for the preparation of various pharmaceuticals, agrochemicals, and other fine chemicals.
Relevance
Its structure and reactivity make it suitable for use as an intermediate in the production of diverse compounds.
Value
Its properties make it valuable in the development of new materials and products.
Check Digit Verification of cas no
The CAS Registry Mumber 446880-80-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,4,6,8,8 and 0 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 446880-80:
(8*4)+(7*4)+(6*6)+(5*8)+(4*8)+(3*0)+(2*8)+(1*0)=184
184 % 10 = 4
So 446880-80-4 is a valid CAS Registry Number.
446880-80-4Relevant articles and documents
COMPOUNDS
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Page 33, (2010/02/06)
The invention relates to novel aminothiazole derivatives which are inhibitors of the transforming growth factor, ("TGF")-? signalling pathway, in particular, the phosphorylation of smad2 or smad3 by the TGF-β type I or activin-like kinase ("ALK")-5 receptor, methods for their preparation and their use in medicine, specifically in the treatment and prevention of a disease state mediated by this pathway.
