4493-01-0Relevant articles and documents
Efficient and reusable CuI/1,10-phenanthroline-catalyzed oxidative decarboxylative homocoupling of arylpropiolic acids in aqueous DMF
Liu, De-Xian,Li, Fei-Long,Li, Hong-Xi,Gong, Wei-Jie,Gao, Jun,Lang, Jian-Ping
, p. 4817 - 4822 (2014)
An efficient method for synthesis of 1,3-diynes through the CuI/1,10-phenanthroline-catalyzed oxidative decarboxylative homocoupling of aryl pioprolic acids in aqueous DMF has been developed. The catalytic system was suitable for a variety of arylpropiolic acids, and the corresponding 1,3-diynes could be prepared in high yields. The catalytic system was recovered from the organic products by filtration and its aqueous DMF filtrate retained good activity even after at least four cycles of use.
Facile synthesis of 3, 3′-disubstituted 2, 2′-binaphthyls by transition-metal-catalyzed double benzannulation
Umeda, Rui,Tabata, Hiromasa,Tobe, Yoshito,Nishiyama, Yutaka
supporting information, p. 883 - 884 (2014/06/23)
3, 3′-Disubstituted 2, 2′-binaphthyls were prepared by the Cuor Re-catalyzed double benzannulation reaction of 2-(phenylethynyl) benzaldehyde with various butadiynes in the presence of trichloroacetic acid, in moderate to good yields. Acceleration of the second benzannulation was clearly observed.
Rh(I)-catalyzed decarbonylation of diynones via C-C activation: Orthogonal synthesis of conjugated diynes
Dermenci, Alpay,Whittaker, Rachel E.,Dong, Guangbin
, p. 2242 - 2245 (2013/06/05)
Utilization of C-C bond activation as a unique mode of reactivity for constructing C-C bonds provides new strategies for preparing important organic molecules. Development of a Rh(I)-catalyzed C-C activation of diynones to synthesize symmetrical and unsymmetrical conjugated diynes through decarbonylation is reported. This C-C cleavage strategy takes advantage of the innate reactivity of conjugated ynones without relying on any ring strain or auxiliary directing group. This alkynation method also has orthogonal properties compared to typical cross-coupling reactions.