44975-82-8Relevant articles and documents
Synthesis of tert-Leucine and Related Amino Acids
Groth, Ulrich,Huhn, Thomas,Porsch, Bettina,Schmeck, Carsten,Schoellkopf, Ulrich
, p. 715 - 720 (2007/10/02)
The 2,5-dialkoxypyrazines 3a and b were prepared in three steps from methyl glycinate hydrochloride (1) in an overall yield of 18 and 63 percent.Upon the addition of lithium organyls to 3b and subsequent acid hydrolysis the ethyl glycinates rac-7 were obtained.Key Words: tert-Leucine / Amino acids / Glycine cation equivalents / Bislactim ether method