454445-45-5Relevant articles and documents
Characterization and crystal structure of a high-affinity pentavalent receptor-binding inhibitor for cholera toxin and E. coli heat-labile enterotoxin
Merritt, Ethan A.,Zhang, Zhongsheng,Pickens, Jason C.,Ahn, Misol,Hol, Wim G. J.,Fan, Erkang
, p. 8818 - 8824 (2007/10/03)
Multivalent ligand design constitutes an attractive avenue to the inhibition of receptor recognition and other biological events mediated by oligomeric proteins with multiple binding sites. One example is the design of multivalent receptor blockers target